Elevated Testosterone Decreases Risk of Asthma

Jinzang

Member
The full article is here.

According to research presented at the American Academy of Allergy, Asthma & Immunology Annual Meeting patients with elevated serum testosterone levels were less likely to have current asthma regardless of gender. Data from the 2011-2012 National Health and Nutrition Examination Survey were evaluated in 7584 patients aged 1 to 80 years old. Of the total study population, 601 patients were identified with current asthma; patients were further stratified by age and gender. Logistic regression analysis was used to determine the association between serum testosterone and the prevalence of current asthma.

In the general study population, each 25 ng/dL increase in serum testosterone correlated with a 3% (95% CI, 1%-4%; P =.002) decrease in the likelihood of having asthma. Dividing the patients into tertiles based on the range of serum testosterone levels, a 58% (95% CI, 29%-75%; P =.003) decrease in the likelihood of current asthma was associated with the highest tertile (n=1904) vs the lowest tertile.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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