E2 and cancer

[JimGainz]

What dose of ai are u currently taking?

It comes out to about .125 mg 3 x week. Very low dose. I can’t stand it when my estrogen gets high. Left unattended, I will hit a 75-80 E2 just on TRT and if I throw in nandrolone it goes to mid 90s. I can’t see any logic behind letting it run wild like this and feel better when I am around 50 or below. I wouldn’t touch an AI if I could maintain an E2 under 50 on my own. I am definitely in the AI camp.

 

[Nelson Vergel]

We will see.

A Repurposing Programme Evaluating Repurposing Transdermal Oestradiol Patches for the Treatment of Prostate Cancer Within the PATCH and STAMPEDE Trials: Current Results and Adapting Trial Design - PubMed

Efficacy results for the M0 cohort (primary outcome measure metastases-free survival) are expected in the final quarter of 2023. For M1 patients (primary outcome measure - overall survival), analysis using restricted mean survival time is being explored. Allied translational work on longitudinal...

pubmed.ncbi.nlm.nih.gov