Does T3 effect GH?

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robs2nd75

Member
Endo added T3 today but she doesn't want me to start until after my GH stim test. Curious if in fact it effects GH and how so?
 
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Neil Olson

New Member
Not sure, but I will tell you from experience. Until you get a good balance of all your hormones you still will not feel good. Been on GH for almost a year and just now getting some nature throid and getting off levothyroxine. Getting a doc to even do a T3 test has been a pain. Got an appointment in June for a new endo.
 

robs2nd75

Member
Neil, thanks for your response. I'm not certain what age you are but I am now seeing a Pediatric Endo and couldn't be happier. She really takes the time to listen. I know many Ped Endo's see "older" patients (I am 38). Just a thought as having to fight to get T3 testing is absurd.
 
Growth Hormone accelerates T4 to T3 conversion. What this means is that if you are taking growth while dieting, you will make more T3 out of your available T4. This is due to the GH having an effect on elevating the enzyme 5'deiodinase. The problem with this is that it works great for a few weeks, but then the T4 begins to run a bit low and you can no longer convert much T3. So, the remedy is to add in some T4 with your T3. Besides, T3 downregulates (decreases) the 5'deiodinase enzyme that is converting the T4 to T3. This is a negative feedback similar to the testes-hypothalamus-pituitary when testosterone is elevated from testosterone injections.

So, the GH accelerates fat loss for a few weeks at an unbelievable rate...and then seems to slow down or even stop. By supplying your system with mostly T4 and just a bit of T3, you allow the GH you are spending all that money on to keep making more T3 from the T4 by way of elevating that great enzyme 5'deiodinase. The amount of T3 you will need will be lower than if you tried to get cut-up on T3 alone, somewhere in the neighborhood of 25mcg total. Maybe less. The T4 will be somewhere between 50 and 100mcg/day. Remember, information purposes only. These are interesting...theories. Don't think I ever got to a legitimate 4% by using these techniques.
 
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