Does losing weight change testosterone levels?

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Henry

Member
Hi,
When I started Androgel, 4 pumps with HCG EOD @ 300iu's, these were my numbers. All from Labcorp:
7/2014 - 585 & no free T measurement
10/2014 - 506 & 11.9
2/2015 - 697 & 16.7
5/2015 - 660 & 24
I get tested twice a year and I was around 227 pounds during that time.

I decided to lose some weight and cut sugar, soda, candies, etc. I just got tested and this was the result:
4/2016 - 1045 & 24.6

Doc is saying that it's too high and wants to drop me down to 3 pumps. I talked him into keeping me at 4, telling him that I don't have any sides and it's probably a fluke. I showed him something on the internet that shows how transdermal T levels fluctuate and he said OK but the next time he tests me, if I go to the top of the range again, he'll change it.

What could have caused this? I weight 187 now. Could the 40lbs weight loss cause my T levels to go up?
 
Defy Medical TRT clinic doctor
Henry, good question. I don't have the answer, but I'm wondering if your body is absorbing the T better. If losing weight (fat) has helped.
 
First congratulations on the weight loss, second the fat loss might mean your converting less to estrogen leaving you with more testosterone or at least a better testosterone to estrogen ratio.
Do you feel better?
 
I also wondered this. I've lost weight since my last bloodwork (about 20lbs) and I'm wondering if it will have an impact on my T and E2 numbers. Bloodwork being done again soon, so we'll see (dose changed only slightly since my last test).
 
I would make sure your test is LC/MS instead of ECLIA (immunoassay). I had one with the cheaper tests (immunoassay) and it had my number over 1000. LC/MS had it in the 700s (about 4 weeks apart).

Pulled from another post on here (note the last part):

Frequently Asked Questions: Testosterone by ... - LabCorp (link wouldn't go out b/c I don't have enough posts)

Types of blood tests for testosterone

There are two types of blood tests frequently used in gauging your testosterone production and retention levels: the LC/MS method and the ECLIA method.
LC/MS

LC/MS, or liquid chromatography-mass spectrometry, is the Mercedes-Benz of blood testing for testosterone. The CDC classifies LC/MS testing as the most reliable method for testing your total testosterone level. (Quest Diagnostics) LC/MS is also extremely sensitive, which makes it the preferred method for testing patients with chronically low testosterone levels.

ECLIA

ECLIA is the more widely-used blood test by clinics to gauge your total testosterone. ECLIA (Electrochemiluminescent Immunoassay) is quick and far more affordable that LC/MS. Unfortunately, ECLIA also tends to register testosterone levels as being higher than they truly are.
 
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Most people would say so, but it hasn't necessarily been my experience. If I lose fat weight only, I don't notice a change. But if I lose, say, 10 pounds of fat and put on 5 pounds of muscle, then I do notice a change.
 
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