Does anyone have any experience using Niagen?

[kd4re]

I just saw my Endocrinologist today and he's recommending that I try Niagen.

 

[Nelson Vergel]

I know nothing about this supplement but this is what I found (most data in mice)

Results from First Human Clinical Study Demonstrate ChromaDex's NIAGEN(R) Nicotinamide Riboside Effectively Increases the Co-enzyme NAD+ and is Safe

They just started a larger study in humans

ChromaDex Initiates Second Human Clinical Study on NIAGEN® -The World’s First and Only Commercially Available Form of Nicotinamide Riboside (NR)

 

[Nelson Vergel]

The Youth Restoring Benefits Of NAD+

 

[Nelson Vergel]

Now you got me really curious !

IV infection decreases intracellular nicotinamide adenine dinucleotide [NAD].
Murray MF, Nghiem M, Srinivasan A.
Biochem Biophys Res Commun. 1995 Jul 6;212(1):126-31.

PMID: 7611995
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Select item 77632682.
Nicotinamide inhibits HIV-1 in both acute and chronic in vitro infection.
Murray MF, Srinivasan A.
Biochem Biophys Res Commun. 1995 May 25;210(3):954-9.

PMID: 7763268
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Select item 114485903.
Increased plasma tryptophan in HIV-infected patients treated with pharmacologic doses of nicotinamide.
Murray MF, Langan M, MacGregor RR.
Nutrition. 2001 Jul-Aug;17(7-8):654-6.

PMID: 11448590
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Select item 145222634.
Tryptophan depletion and HIV infection: a metabolic link to pathogenesis.
Murray MF.
Lancet Infect Dis. 2003 Oct;3(10):644-52. Review.

PMID: 14522263
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Select item 125673035.
Nicotinamide: an oral antimicrobial agent with activity against both Mycobacterium tuberculosis and human immunodeficiency virus.
Murray MF.
Clin Infect Dis. 2003 Feb 15;36(4):453-60. Epub 2003 Jan 31. Review.

PMID: 12567303 Free Article

 

[Nelson Vergel]

26 out of 86 people said they felt nothing. Anecdotal efficacy; 70 %

I am not sold yet and won't try it.


https://www.amazon.com/Niagen-Nicot...00K6W5SMW/ref=cm_cr_arp_d_product_top?ie=UTF8

 

[PAUL-E]

Got me really curious as well

 

[PAUL-E]

26 out of 86 people said they felt nothing. Anecdotal efficacy; 70 %

I am not sold yet and won't try it.


https://www.amazon.com/Niagen-Nicot...00K6W5SMW/ref=cm_cr_arp_d_product_top?ie=UTF8

Nelson do you think given the supplement industries reputation for quality control and under dosing could be a contributing factor? also wounding if IV or IM would be more effective.

 

[kd4re]

My endocrineologist says it gives him energy and he's happy with the results

 

[Nelson Vergel]

My endocrineologist says it gives him energy and he's happy with the results

Let us know how it works for you! Thanks

 

[Nelson Vergel]

Nelson do you think given the supplement industries reputation for quality control and under dosing could be a contributing factor? also wounding if IV or IM would be more effective.

It is actually the patented product that is sold on Amazon

 

[Nelson Vergel]

Got me really curious as well

This is the same guy that developed resveratol which was later not found to work after GSK paid millions for its rights. GSK dropped the drug later. Umm...

https://en.wikipedia.org/wiki/David_Andrew_Sinclair

 

[PAUL-E]

ok thanks nelson. kd4re let us know what your experience with it is good or bad.

 

[PAUL-E]

This is the same guy that developed resveratol which was later not found to work after GSK paid millions for its rights. GSK dropped the drug later. Umm...

https://en.wikipedia.org/wiki/David_Andrew_Sinclair

LOL I didn't know that Umm... is right

 

[kd4re]

Okay I will.

 

[kd4re]

okay i will