Do DHT derivatives like Anavar / Oxandrolone upregulate 5 Alpha Reductase / 5AR?

[Anonymon]

Finasteride is what originally lead me to all of this. Reading into things more lately, I read some people saying that the presence of 5AR metabolites like DHT up regulate 5AR in a positive feedback loop. Does anyone have any knowledge or experience with this?

 

[Nelson Vergel]

We discussed this here:

TRT Effect on 5 Alpha Reductase and Upstream Hormones- Cause of Low Mood and Anxiety? - Excel Male Health Forum

In this video dr Mark Gordon, starting at 9min, explains how using good level of TRT can "burn" 5 alpha reductase enzyme, that beside being responsible for converting Test into DHT, it is also responsible for converting Progesterone into Allopregnanolone in the brain. Throughout the...

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