Abstract Context: Injections with intramuscular testosterone esters have been available for almost 8 decades and not only result in predictable serum testosterone levels but are also the most inexpensive modality. However, they are difficult to self-administer and associated with some discomfort. Recently, subcutaneous administration of testosterone esters has gained popularity, as self-administration is easier with this route. Available data, though limited, support the feasibility of this route. Here we review the pharmacokinetics and safety of subcutaneous testosterone therapy...
As we all know, sustained release, long acting preparations are not the only way to achieve more sustained stable serum concentrations. More frequent injections of the common Test Cyp would likely achieve similar results with similar metabolic benefits. And we can add less aromatization and less erythrocytosis to the benefit list. Personally I am injecting TC 4 days per week.
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