GLP-1 Therapy Clinical Guide Preventing Muscle Loss During Treatment & Weight Regain After Discontinuation Evidence-Based Strategies with Annotated References
Executive Summary
GLP-1 receptor agonists (semaglutide, tirzepatide, liraglutide) have revolutionized obesity treatment, producing weight losses of 15-25%. However, two critical challenges require proactive management: preserving lean muscle mass during treatment and preventing weight regain after discontinuation. This guide synthesizes current evidence and provides actionable clinical...
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