Clomid +Tamoxifen PCT - When to schedule bloodwork?

Charbrisc

New Member
Hey everyone. I am 32 years old and have been trying to come off of TRT. I was put on it in my early 20's erroneously. I was very underweight and overtrained, which is why I believe my T was so low. My doctor immediately put me on TRT and I didn't know anything so I started.

My wife and I decided we wanted to get pregnant two years ago so I started HCG and slowly came off of TRT. My last bloodwork showed Total T of 550 and free T in the low end of normal (E2 was also in the low end of normal).

So, I decided I want to try and come off of everything and have started Scally's PCT protocol. My question is when should I get bloodwork to make sure everything is going okay.

I have been on clomid (25mg ED) plus tamoxifen (20mg ED) for close to 6 weeks now. Should I stop both of these and then get bloodwork or get bloodwork before I come off of them? What all should I check? LH, FSH, Total T, Free T, E2, SHBG, prolactin? Anything else?

The reason I ask about bloodwork timing is because in one of Scally's protocols he suggested to stop both Clomind and Tamoxifen for about 2 weeks and then get tested. But, I wasn't sure if I should get bloodwork while on them (I believe I have seen Dr. Saya say this) to make sure things are working (they were while on HCG) and then taper off?

Lastly, I have noticed more energy and mental clarity with clomind + tamoxifen as compared to HCG mono, but my libido is way worse. What might be the reason for these differences?

Thanks so much!
 
Would check levels while still on...then check levels after off for 6-8 weeks to compare/contrast.

The subjective difference you mention between HCG/clomid could be due to many variables, the most likely being: different hormone levels (T/E) and also the E receptor interactions of clomid (mixed agonist/antagonist).
 
Would check levels while still on...then check levels after off for 6-8 weeks to compare/contrast.

The subjective difference you mention between HCG/clomid could be due to many variables, the most likely being: different hormone levels (T/E) and also the E receptor interactions of clomid (mixed agonist/antagonist).

Thanks so much, Dr. Saya! Are there any other tests you would recommend in addition to the ones I listed?

Also, if things look okay, would you recommend dropping Clomid down completely or slowly decrease? If the latter, I assume I would go to 12.5mg daily and then to EOD? Over what time period?

Sorry for all the questions:) I appreciate your help!
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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