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brizspot

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Morning. I am a Defy patient and awaiting my 90 day follow up with Dr. Calkins. Attached is my recent bloodwork. Generally feeling well, but erections are hit and miss, and there seems to be some lag time between arousal and getting erect. Also not as hard as should be in my opinion. Just not clicking all the way. Morning wood is present, but not always fully erect. Anxiety too. Could my E2 be still slightly too high?
My protocol:
40mg test cyp every 3.5 days
400iu hcg every 3.5 days
.125 mg anastrazole every 3.5 days
(all done at same time)
Hope to hear your views. Thanks in advance.
 

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  • LAB RESULTS 7.26.18 (3).pdf
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Defy Medical TRT clinic doctor
You may want to remove your name/DOB?

Your TT/FT looks good and your SHBG is slightly just above the mid-range (range 16.5-55.9) so the mean (mid range) is 36.2

Your e2 (sensitive assay) is slightly elevated and may be too high for you, too low or too high e2 can have negative effects on libido/erectile function as we know estradiol is needed in healthy amounts as it has many positive benefits on ones (mood/libido/erectile function/immune system/bone health).

You will have to discuss this with Dr. Calkins at your follow up as adjustment to your a.i. dose may be needed.
 
Thanks Madman I will do that! Gut feeling is
You may want to remove your name/DOB?

Your TT/FT looks good and your SHBG is slightly just above the mid-range (range 16.5-55.9) so the mean (mid range) is 36.2

Your e2 (sensitive assay) is slightly elevated and may be too high for you, too low or too high e2 can have negative effects on libido/erectile function as we know estradiol is needed in healthy amounts as it has many positive benefits on ones (mood/libido/erectile function/immune system/bone health).

You will have to discuss this with Dr. Calkins at your follow up as adjustment to your a.i. dose may be needed.
Thanks Madman I will do that! Gut feeling is that my E2 is little high as well.
 
YOu should be on a Cyp dose reduction instead of the AI. Your Free T is way over the lab range and that ought to be where you look not taking more AI, which will probably be the default way to address the high(er) E. 38.3 may be too high for you but like I say I'd rather see a Cyp dose of 35mg E3.5D
 
YOu should be on a Cyp dose reduction instead of the AI. Your Free T is way over the lab range and that ought to be where you look not taking more AI, which will probably be the default way to address the high(er) E. 38.3 may be too high for you but like I say I'd rather see a Cyp dose of 35mg E3.5D
Vince I thought the same as well. I will obviously propose that to Dr Calkins. I started at .45mg test twice a week and 500 iu hcg twice per week originally. Started having high E2 symptoms measuring E2 at 44. Should I try the reduction on my own since I do not have my consult for about 2 weeks?
 
Or even increase the anastrazole to see if there is an improvement for the meantime? Maybe .25mg twice per week?

Vince makes a great point as lowering ones dose slightly could bring down the e2 and maybe eliminated the use of an a.i., again it is best to wait for your follow up with Dr. Calkins to discuss what the best move would be.
 
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