Cardiovascular disease, osteoporosis and HRT

madman

Super Moderator


This video features an interview with Professor Marco Gambacciani, a menopause specialist from Italy, discussing the importance of hormone replacement therapy (HRT) in reducing the risk of cardiovascular disease and osteoporosis in women. They highlight the lack of awareness and access to evidence-based treatments for menopause symptoms in many countries, including the UK and Italy. They emphasize the need for women to have bone density scans and to consider HRT, especially when started at a younger age, to prevent future diseases and improve quality of life.


Key takeaways:


*Professor Marco Gambacciani highlights the importance of hormone replacement therapy (HRT) in reducing the risk of chronic diseases in menopausal women, including cardiovascular disease and osteoporosis.

*The lack of awareness and access to evidence-based treatments for menopausal symptoms in the UK and Italy is concerning.

*Bone density scans are important in identifying women at risk of osteoporosis and fractures, and should be done around the time of menopause.

*Treating menopausal symptoms, such as hot flashes and night sweats, with hormones can also prevent chronic diseases in women.

*The longer a woman is without hormones, the greater her risk of heart disease and other chronic diseases.

*Hormone replacement therapy should be started around the time of menopause to prolong the beneficial effects of endogenous estrogens.

*The prescription and availability of HRT in many countries, including the UK and Italy, needs improvement.

*HRT has been shown to reduce symptoms, improve quality of life, and maintain vaginal function and enjoyable sex in menopausal women.

*Healthcare professionals should be knowledgeable about HRT and its benefits in order to provide appropriate care to menopausal women.

*Women should be empowered to make informed decisions about HRT based on their individual needs and risks.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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