Expected discouragement has set in after getting my CAC score update.
Everything I could think of in my power to shunt my last CAC test in the opposite direction has apparently failed when I saw that my score has essentially tripled in the last three years.
Something has gone askew, against what I had mapped out, against every conceivable supplement, dietary intervention and exercise routine I could think of.
What the hell is left? More aggressive fasting? CR? Done all THIS and more.
Wheat, gluten, soy, yeast, sugar, trans fat, seed oil free, organic, grassfed, LCHF pastured, whole foods diet.
In 2014, my score was ZERO. In 2018, 9.03 in the LAD (widowmaker artery) – the warning light started!
Latest: 25 in the LAD (sh*t!) and 3 in the RCA
What could possibly be left that I’m doing WRONG to warrant further plaque progression?
Genetically cursed with those SNPs I mentioned?
Still unoptimized thyroid function? Elevated TSH with normal FT3, FT4, TPO, TgAb.
Taking 90mg NP Thyroid despite the recent recalls as I didn’t think the 10-15% drop in potency would have made that much difference. Maybe I was wrong?
– dose change?
– switch to compounded NDT?
– switch to pure T4 (Tirosint)?
– better off not changing; not going to make a difference? T4 meds definitely not going to help reduce lipids?
Gut issues?
Fasting glucose? Latest OGTT w/ fasting insulin was pretty good, showed robust insulin response. Last a1c: 5.1
Excess adiposity?
Inflammation? hsCRP has never been <1.5 for last 20 years; nothing I've tried to date has ever reduced that.
Hi-dose delayed-release niacin (Endur-acin) – raise liver enzymes
Lipid markers would be the first place I'd look and that's where the problems are:
Off the top:
– Pattern B
– sdLDL-P
– Lp(a)
-Trigs
Low normal HDL
If sdLDL-P is a main trigger and then maybe look at PCSK9 inhibitors as an alternative to statins?
Until I discover what the driving force in my case is, how will I know what path to reverse it to focus on?
Everything I could think of in my power to shunt my last CAC test in the opposite direction has apparently failed when I saw that my score has essentially tripled in the last three years.
Something has gone askew, against what I had mapped out, against every conceivable supplement, dietary intervention and exercise routine I could think of.
What the hell is left? More aggressive fasting? CR? Done all THIS and more.
Wheat, gluten, soy, yeast, sugar, trans fat, seed oil free, organic, grassfed, LCHF pastured, whole foods diet.
In 2014, my score was ZERO. In 2018, 9.03 in the LAD (widowmaker artery) – the warning light started!
Latest: 25 in the LAD (sh*t!) and 3 in the RCA
What could possibly be left that I’m doing WRONG to warrant further plaque progression?
Genetically cursed with those SNPs I mentioned?
Still unoptimized thyroid function? Elevated TSH with normal FT3, FT4, TPO, TgAb.
Taking 90mg NP Thyroid despite the recent recalls as I didn’t think the 10-15% drop in potency would have made that much difference. Maybe I was wrong?
– dose change?
– switch to compounded NDT?
– switch to pure T4 (Tirosint)?
– better off not changing; not going to make a difference? T4 meds definitely not going to help reduce lipids?
Gut issues?
Fasting glucose? Latest OGTT w/ fasting insulin was pretty good, showed robust insulin response. Last a1c: 5.1
Excess adiposity?
Inflammation? hsCRP has never been <1.5 for last 20 years; nothing I've tried to date has ever reduced that.
Hi-dose delayed-release niacin (Endur-acin) – raise liver enzymes
Lipid markers would be the first place I'd look and that's where the problems are:
Off the top:
– Pattern B
– sdLDL-P
– Lp(a)
-Trigs
Low normal HDL
If sdLDL-P is a main trigger and then maybe look at PCSK9 inhibitors as an alternative to statins?
Until I discover what the driving force in my case is, how will I know what path to reverse it to focus on?
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