Bloodtest result back, test high but have all the symptoms of low test

Are there any large controlled trials demonstrating these cures? The stuff regarding MS sounds promising, but science doesn't accept anecdotes as evidence. The cited paper also contains some hand waving and assumptions that go beyond the available evidence. As an aside, aren't receptor polymorphisms a separate issue compared to low serum levels relative to dose? Is the claim that there's insufficient 25-hydroxylation in the liver? In any case, the larger controlled trials are failing to find benefits in supplementing vitamin D, and even point to the possibility of harm at higher levels. The reality is that most people should not be concerned unless their levels naturally fall below 20 ng/mL.
The German clinicians/researchers who wrote the paper are using Dr. Coimbra's protocol to treat patients with MS. We all understand that there can be quite a lag time between what is accepted by science/medicine and what results practitioners are seeing in patients. The polymorphism theory, in essence, states that the receptors, for some reason(s), aren't sensing the vitamin D(or thyroid or testosterone), thus higher or supraphysiolgic doses are needed to overcome that cellular resistance.

To be clear; I'm stating what I'm doing, based on much reading, including reports from people who reversed or cured autoimmune issues with high dose vitamin D & K2. Most of us on this site are intelligent and well versed in the science of hormone replacement and related protocols, as well as nutrition. And, we can agree to disagree.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
5
Guests online
143
Total visitors
148

Latest posts

Back
Top