Block T to E conversion, take E instead?

eli

Active Member
So I had an idea for people who aromatize too much, HyperAromatization.

What if one takes an AI to block conversion of Testosterone to Estrogen and takes Estrogen instead.
you say, why? Because this way you control how much estrogen you want. A lot of people on TRT just have no control on how much they aromatize. You control how much Testosterone and Estrogen your body needs. You pick the ratio! Doesn't matter how much fat you have, or if you convert too much. This would result in a lower Testosterone intake too. Lots of free T and DHT.

Would this actually work?
 
No, oestradiol has autocrine, paracrine and endocrine effects. You would not be able to effectively titrate the oestradiol at tissue level. Oestrodiol has numerous tissue specific protective effects.

Dr Robert Stevens
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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