Better to dose before, or after major blood draw?

Helboi

New Member
So I have high hematocrit and I'm going in to have therapeutic phlebotomy done on Friday. My T dose is usually done in the early morning, which will be before the blood draw. My question is: would it be better to wait until after the blood draw to dose, or should I stay on my usual schedule? I worry that removing that much blood after my dose will also take a bunch of T out of my system...but maybe my medical/science knowledge needs to be updated and this will have little to no effect.
 
So I have high hematocrit and I'm going in to have therapeutic phlebotomy done on Friday. My T dose is usually done in the early morning, which will be before the blood draw. My question is: would it be better to wait until after the blood draw to dose, or should I stay on my usual schedule? I worry that removing that much blood after my dose will also take a bunch of T out of my system...but maybe my medical/science knowledge needs to be updated and this will have little to no effect.
I know we inject in the fat or muscle, so I would think after injecting it would be okay to donate blood, but I would be very interested to see what others have to say.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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