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ZoomyR6

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Hey guys,

Ive been on TRT for about 1.5 years now trying all different protocols. My lates was 70mg 2x/wk (Monday morning and thursday evening) for a total of 140mg/wk via slin syringe shallow IM. Adex at .25mg 24hrs after injection.
Prior, I wasn't using adex and my E2 was at 90 (range <30)
I am used to Quest labs but this time they were send to a different lab with slightly different numbers. Lately I have been feeling slightly tired but no joint pain whatsoever. I have been having increase heart rate with accompanying anxiety. I am having a hard time with getting/maintaining erections and my morning wood is non existent. When it does come, my sensitivity isn't there. I went limp the other night during sex after a while. The labs now after the small amount of adex added is:

Prolactin- 13 (4-15.2) Will this go down on its own eventually?
Estradiol- 14.7 (11.3-43.2) I usually get LC/MS/MS but dont see which one on these labs)
Total T-658.2 (249-836)
SHBG-14.2 (16.50-55.90)
Free T-18.76 (2.29-20.70)
Bio T-498 (15-575

As I said, I shoot monday morning and thursday evening. These were taken in office on wednesday morning. In the past with Quest, my trough TT was above normal.

I am guessing low E2 to be the blame for my symptoms but usually low E2 would have strong morning wood. I would have thought my e2 was elevated due to the anxiety and increased heart rate.

One last thing, I usually get my TT read with a sensitive assay LC/MS/MS which throws a lot higher number than the standard assay. Which one is the normal one to go by?
 
Defy Medical TRT clinic doctor
I agreed your estrogen levels are too low. I would consider more frequent injections because of you low shbg.
When you have low shbg, most men do better with more frequent injections. Some members find that when having low shbg, they do do better with lower estrogen levels.
 
I agree with others, you should increase injection frequencies do to low SHBG, you're urinating test into the toilet. This is why lower SHBG guys do much better on an EOD or everyday protocol.

My SHBG isn't as low as yours (low 20's) and I do well on an ED or EOD protocol, a twice weekly protocol doesn't show good results for me.

Your anxiety is likely caused by low estrogen, emotions may even be blunted to some extent.
 
Thanks guys. Any idea which is the MAIN cause of the wood problems I've been having?
I really dont want to do more than 2 injections a week
 
Thanks guys. Any idea which is the MAIN cause of the wood problems I've been having?
I really dont want to do more than 2 injections a week

Your main problem is these large twice weekly injections is the driving factor in why your estrogen levels are so high and you're having to throw a bunch of drugs at the problem, I had the same problem and is why I'm injection 21mg every 2 days, no AI.

You may have no choice but to inject EOD or ED or you may continue to have these problems.
 
Frequent injections become second nature once the need for them is accepted. Should you choose to adopt a more frequent protocol, you will be comfortable with the entire process in a very short time.

You wrote you've followed many different protocols; all of them incorporate twice weekly injections?
 
Frequent injections become second nature once the need for them is accepted. Should you choose to adopt a more frequent protocol, you will be comfortable with the entire process in a very short time.

You wrote you've followed many different protocols; all of them incorporate twice weekly injections?
Yes. 1x week wasnt good. My shbg was even lower
 
The conclusion is the further away you get from a weekly protocol, the better you will feel. The more frequent the better your chances are of feeling good, this is my experience.
This I get and thank you.
However, right now I am concerned with my ED issues. It's starting to ruin a brand new relationship.
I need to raise my E2 I'm assuming and dont know how to do so quickly and how long it will take.
Does Cialis work when E2 is low.
 
Thanks guys. Any idea which is the MAIN cause of the wood problems I've been having?
I really dont want to do more than 2 injections a week

My E2 has been low lately, and I don’t really experience morning wood often. It’s probably a mix between too low E2, and not high enough free testosterone. The ratio is just off. You might benefit from not only getting E2 up a bit, but getting free T up a bit as well. But just getting E2 up could definitely do the trick. Trial and error is the only real way to tell.
 
This I get and thank you.
However, right now I am concerned with my ED issues. It's starting to ruin a brand new relationship.
I need to raise my E2 I'm assuming and dont know how to do so quickly and how long it will take.
Does Cialis work when E2 is low.

You could stop taking the ai all together temporarily, and up your testosterone dose a little bit. E2 will come back pretty quickly.

If increasing testosterone dosage a little isn’t an option, I would just stop the ai all together. Then wait for morning wood to come back, and for libido to increase, and for ED to improve, and then start taking the ai again, but at about half the dose, maybe even less. But I would stop taking the ai all together and wait for symptoms to resolve, before taking another dose of ai.

I’m in a similar boat. E2 is on the low side, and my libido is in the toilet, and I get soft easily without constant stimulation, and extreme brain fog, and some lethargy. I stopped taking the ai a few days ago, upped my testosterone dose, and am going to wait for libido to return before I get back on an ai. I might see if I can go without it all together. But if I do take it again, it’s gonna only be after my libido and strong erections return.
 
Just take 5-10 mg Cialis daily for two weeks and see if you get your erections jump started. No need to suffer from bad sexual performance.
 
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Just take 5-10 mg Cialis daily for two weeks and see if you get your erections jump started. No need to suffer from bad sexual performance.
Will do, I have some on the way, thanks.
I'm having bad anxiety which i forgot to mention. Hopefully during the period of cialis, my e2 will go back up.
 
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