Arimidex Dose and Timing

[meelord]

Got my blood work back and wanted some input. Currently on Test C 100 mg/ml a week taken every third day with 250 iu HCG. I have been taking Arimidex .5 mg EOD.

Got my blood work back. Timing as follows:

Tuesday
Took​ 50ml Test C
250 iu HCG
.5 Adex

Thursday
.5 Adex 5 am
Blood draw 10 am

Test results:

Test total=1141 ng/dl (high but in range)
Free test=26.2 (out of range high side)
Estradiol=6.8 (out of range low side)
SHBG=31.9 (normal)

Any thoughts and feedback would be appreciated. How do I feel? Pretty good. I generally have morning wood and can have sex. However, and I know this may sound weird, I just don't feel that horny. I can have sex to climax but I do think my sensitivity has been diminished. I assume everybody is going to say that be it's because my estradiol is low. I suppose that is the most logical explanation.

I should add however that's sometimes after taking the Arimidex I do feel good and I have avoided having itchy nipples. I was wondering if having dosed myself with Arimidex five hours before the test that I ended up giving myself an artificially low rating even though I know the half life is 50 hours. For what it's worth I think the HCG is what spikes my estradiol, but it feels like the HCG is critical for libido. What is more frustrating is that my body composition isn't changing that much even though I am working out, I.e., I am not dropping that much fat.

Most importantly do people feel like I have driven my estradiol too low with my dose of Arimidex even though I clearly have not crashed my estradiol? Would my libido and penis sensitivity be better with a smaller dose of Arimidex?

In addition given the timing of my HCG injection and it's relatively short half-life do you think I am seriously spiking my testosterone far above my test readings for the day or two immediately following my injection? Which is to say the total testosterone reading is close to a trough reading and I am afraid I might be way above that reading most of the time. Would anyone recommend a different dosing regimen? Is this even something to worry about?

 

[CoastWatcher]

Why in the world are you suppressing your estradiol to that extent? Did you have elevated levels, on the sensitive test, accompanied by symptoms? Even if you did, your levels are remarkably unhealthy for any man.

 

[lowe2sucks]

what happens often if you get your e2 really low it doesnt hit you right away (low e2 symptoms) but after some time it hits you like a train.. anything lower then 20 pg/ml is pretty dangerous to be..

 

[johndoesmith]

You've crashed your E2 and probably don't need arimidex.

So many men are obsessed with "blocking their estrogen". I don't know why, I guess it's paranoia, but estrogen is a necessary hormone for male sexual function and general health. Suppressing it to low levels like you're doing is a good way to cause misery.

 

[Vince Carter]

.5mg EOD is a whopper MEGA dose...WTF

 

[meelord]

On my ultrasensitive test from Kaiser several weeks ago my E2 was 62 when according to their test I should be sub 29. I tend to convert. I have stopped the Arimidex, but I am grateful I have it on hand. Over the years I have definitely dealt with high E2 symptoms and I feel like most of the HRT docs have been clueless on E2 control until the last five years. For many years I feel like much of the benefit of TRT was negated by high E2. So much so I stopped. Any way that is my own experience and I don't want to extrapolate it out to other readers.

Nevertheless I feel like this site can seem relentlessly anti estrogen control. That said, I also want to acknowledge that the HRT community has a tendency towards a "more is better" approach to almost everything and Arimidex can be highly dangerous for those folks.

 

[meelord]

62 on a ultrasensitive Kaiser test when normal is <29

 

[Vince]

You may have already read this thread. https://www.excelmale.com/forum/showthread.php?2309-Role-of-Estradiol-in-Men-and-Its-Management

 

[Vince Carter]

On my ultrasensitive test from Kaiser several weeks ago my E2 was 62 when according to their test I should be sub 29. I tend to convert. I have stopped the Arimidex, but I am grateful I have it on hand. Over the years I have definitely dealt with high E2 symptoms and I feel like most of the HRT docs have been clueless on E2 control until the last five years. For many years I feel like much of the benefit of TRT was negated by high E2. So much so I stopped. Any way that is my own experience and I don't want to extrapolate it out to other readers.

Nevertheless I feel like this site can seem relentlessly anti estrogen control. That said, I also want to acknowledge that the HRT community has a tendency towards a "more is better" approach to almost everything and Arimidex can be highly dangerous for those folks.

Yet you post a 6.8 E2...and think we're anti-Estrogen control. You've little idea what you're doing and the proof is right here.

 

[johndoesmith]

Yet you post a 6.8 E2...and think we're anti-Estrogen control. You've little idea what you're doing and the proof is right here.

You owe me a car detailing. I just spit my drink all over the car. .

 

[meelord]

Lighten up Francis. That said, I also want to acknowledge that the HRT community has a tendency towards a "more is better" approach to almost everything and Arimidex can be highly dangerous for those folks.

 

[meelord]

That is so funny.

 

[johndoesmith]

On my ultrasensitive test from Kaiser several weeks ago my E2 was 62 when according to their test I should be sub 29. I tend to convert. I have stopped the Arimidex, but I am grateful I have it on hand. Over the years I have definitely dealt with high E2 symptoms and I feel like most of the HRT docs have been clueless on E2 control until the last five years. For many years I feel like much of the benefit of TRT was negated by high E2. So much so I stopped. Any way that is my own experience and I don't want to extrapolate it out to other readers.

Nevertheless I feel like this site can seem relentlessly anti estrogen control. That said, I also want to acknowledge that the HRT community has a tendency towards a "more is better" approach to almost everything and Arimidex can be highly dangerous for those folks.

This site is anti-reckless estrogen "control".

Your estrogen has been "controlled" into the ground. It nearly doesn't exist. The risk of osteoporosis, depression, ED, anhedonia, and just pure misery is really high at single digit levels.

 

[meelord]

Seriously I appreciate the thoughtful and measured feedback.

 

[meelord]

All right Vince you were 100% right...E2 crashed... Lesson learned. Woke up last night with muscle and joint pain so bad I thought I had the flu. Fortunately I had only been taking Arimidex for a few weeks and I hope my E2 will rebound. In my case, I started to feel better once my E2 started dropping but I clearly overshot. Major fatigue and mild constipation lead me to see mistake. I know appreciate this sites more conservative views on E2 control. Apologies.

 

[FeelingLost]

Thanks for posting your progress or lack of meelord, folks like me, thinking about asking for Arimidex because my E2 tests high and I feel like most of the good feeling I was getting as my TT was slowly going up and now has been muted do to E2. Chasing a good E2 number seems to be more difficult than finding the right TT/FreeT number.
I am slowly loosing faith I will ever get there.

 

[meelord]

I don't want to say forget Arimidex, but as has been said repeatedly on this site, be cautious, start at a very low dose and do your blood work.

 

[meelord]

You may have already read this thread. https://www.excelmale.com/forum/showthread.php?2309-Role-of-Estradiol-in-Men-and-Its-Management

I did read it. What is your preferred dosing schedule Test Cyp and HCG?

 

[CoastWatcher]

I did read it. What is your preferred dosing schedule Test Cyp and HCG?

For nearly two years I have been injecting 16mg of testosterone enanthate every morning, and 250 of HCG twice a week. Testosterone at or above 1000, e2/sensitive in the high 20s/low 30s. No AI. In fact, I went to the daily injection schedule to achieve a steady-state testosterone level and avoid Anastrozole. I was successful. Energy, libido, concentration, mood, and erectile function are excellent. I discontinued citrulline and arginine some time ago, though I take five milligrams of daily Cialis, NAC, CoQ10, and vitamins B12, D, and C.

 

[meelord]

CW that is really helpful information. Thank you. Did you ever consider moving to daily injections of HCG for the same reason...that is to ensure more stable levels and avoid spiking E2? My intuition is telling me that my E2 levels are being bounced around more by my HCG injections then by my T injections.