Anti-Aging Startups

Jinzang

Member
This article tells how anti-aging startups are getting attention from investors:

The primary game plan at Juvenescence, explains Bailey, is to come up with various operations engaged in developing new anti-aging drugs. Juvenescence AI is a joint venture they’ve just set up with Alex Zhavoronkov, who runs Insilico Medicine, based in Baltimore. Mellon met Zhavoronkov while he was researching his book, says Bailey, and believes that the tech the scientist developed can illuminate new programs with a better chance of success.
“They are going to take up to 5 molecules from us every year for development,” says Zhavoronkov, an enthusiastic advocate of AI in drug research who’s also been working on some alliances with Big Pharma players. The group has invested about $7 million in the technology so far, he says, getting the JV set up. More will follow.

It turns out that Insilico is just down the street from where I work, on one of the Johns Hopkins campuses. So I checked out their web site. They have a biological age calculator. You plug in your blood work numbers and it calculates your estimated age.
 
Thought I'd try the calculator to see what it said. I'm 56

Aging AI 1.0:
Your predicted age is 45
Your predicted gender is Female

The Aging AI 2.0 calculator didn't work
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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