6000 iu hcg/week new labs estradiol 110!

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So i'm 38 years old, secondary and have had low test for at least a couple years. I decided about a year ago after a ton of reading on the forums that I wanted to get on trt but I need to get the wife pregnant first.


Last year the endo tried a clomid restart for a couple months and my TT went to 600 and E2 to 59 and I had more energy but libido and brain fog remained and after a few months off clomid my TT went back to about 250.

My last testosterone reading 6 weeks ago came back at TT 212, E was <5.1, LH was 6.1 and FSH was 3.2

5 Weeks ago the endo put me on a fertility dose of HCG at 3000iu e3.5d. and libido came up and a little improvement in energy but still have horribe brain fog. The doc wanted to wait 3 months before labs but I started to have more anxiety and a bit of acne so I got my own labs at privatemdlabs.com yesterday and the results have got me freaked out, TT 939 and E2(not the sensative) at 110-I know the sensative is better but it's a lot more $ and from what i've read the regular is usually within 10 or so of the sensative and I just wated and idea of where I was so I figured good enough.

I have a message in to the doc that I want to get arimidex but wanted some opinions for you guys.

What would be a good starting point on the dosage of the AI? I have heard sories of people tanking their e2 with and Ai so I dont want to go from one extreme to the other.

This high dose of HCG is only temporary and hopefully in a couple months ill be on testosterone every e3.5d with 250 iu HCG at the same time and try to keep test low enough to keep my ex between 20-30 to avoid an AI .
 
Defy Medical TRT clinic doctor
WOW that high does will cause excessive estrogen conversion at the very least split the dose up ED or EOD but seem like too much to me, Why not be on TRT with HCG?
Dose anyone know what HCG dosing is more likely to damage the testical's leyden cells?
 
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Thanks for the quick reply!

I tried to get the doc to do Test and HCG but he said he will NEVER do that. I tried to show him some studies that showed I can preserve fertility while on test and low dose HCG(250iu/e3.5d) and he replied that there is probably some small study that shows water increases test levels-hes a smart ass. I was miserable and needed to try somthing so I agreed to do the HCG mono. I would like to find another endo but the closest I found is like 1.5 hr away.
 
Thanks for the quick reply!

I tried to get the doc to do Test and HCG but he said he will NEVER do that. I tried to show him some studies that showed I can preserve fertility while on test and low dose HCG(250iu/e3.5d) and he replied that there is probably some small study that shows water increases test levels-hes a smart ass. I was miserable and needed to try somthing so I agreed to do the HCG mono. I would like to find another endo but the closest I found is like 1.5 hr away.
IMHO you doc is a close minded a$$ who has no real interest in helping you and will probably do more harm than good, if you post your state you live in maybe someone can recommend a competent DR.
have you had your thyroid checked?
check this out
https://www.excelmale.com/forum/sho...e-and-During-Testosterone-Replacement-Therapy

https://www.excelmale.com/forum/sho...e-Testicular-Shrinkage-and-Preserve-Fertility
 
Anastrozol is powerful so I'd start with 0.25 mg twice a week and test again in 4 weeks if you are going to be on the high dose HCG that long.
 
You need a new Doctor.

3000 iu of HCG e3.5 days is absurd and way way over dosed.

A man can increase fertility on HCG at 125 iu daily with no problem.

HCG is estrogenic and more importantly it aroamatases within the testes and AI are very poor in managing it or lowering it.

The symptoms you have are as a result of your elevated estrogen and you can't stay there long as there are health risks associated with it.

You need to get on a lower dose as soon as you can and/or find a new Doctor who understand Testosterone Therapy in men and get the right care.
 
You need a new Doctor.

3000 iu of HCG e3.5 days is absurd and way way over dosed.

A man can increase fertility on HCG at 125 iu daily with no problem.

HCG is estrogenic and more importantly it aroamatases within the testes and AI are very poor in managing it or lowering it.

The symptoms you have are as a result of your elevated estrogen and you can't stay there long as there are health risks associated with it.

You need to get on a lower dose as soon as you can and/or find a new Doctor who understand Testosterone Therapy in men and get the right care.

Concur with everything especially the bold.
 
So i'm 38 years old, secondary and have had low test for at least a couple years. I decided about a year ago after a ton of reading on the forums that I wanted to get on trt but I need to get the wife pregnant first.


Last year the endo tried a clomid restart for a couple months and my TT went to 600 and E2 to 59 and I had more energy but libido and brain fog remained and after a few months off clomid my TT went back to about 250.

My last testosterone reading 6 weeks ago came back at TT 212, E was <5.1, LH was 6.1 and FSH was 3.2

5 Weeks ago the endo put me on a fertility dose of HCG at 3000iu e3.5d. and libido came up and a little improvement in energy but still have horribe brain fog. The doc wanted to wait 3 months before labs but I started to have more anxiety and a bit of acne so I got my own labs at privatemdlabs.com yesterday and the results have got me freaked out, TT 939 and E2(not the sensative) at 110-I know the sensative is better but it's a lot more $ and from what i've read the regular is usually within 10 or so of the sensative and I just wated and idea of where I was so I figured good enough.

I have a message in to the doc that I want to get arimidex but wanted some opinions for you guys.

What would be a good starting point on the dosage of the AI? I have heard sories of people tanking their e2 with and Ai so I dont want to go from one extreme to the other.

This high dose of HCG is only temporary and hopefully in a couple months ill be on testosterone every e3.5d with 250 iu HCG at the same time and try to keep test low enough to keep my ex between 20-30 to avoid an AI .

The standard estradiol test is of no value in men. You read that it is "within 10 or so of the sensitive"...well, in my own case the sensitive test was half the standard value when I had both run as an experiment some time ago. Is your E2 high? Yes, it most probably is, but how high? That's an important question to answer before you introduce anastrozole, a very potent drug. As for where your estradiol should sit, you noted that you wanted it between 20 and 30. However, the range LabCorp reports at the upper end is 35...and some men do well on values slightly higher. There is no magic, one size fits all estradiol value. Sadly, you aren't getting the medical care you deserve. If you were these points would have been discussed with you, and you would never have been put on a wild-eyed 6000iu/hcg protocol. Gene's point is a good one - find a new doctor and realize the benefits of a well-designed TRT protocol.
 
You need a new Doctor.

3000 iu of HCG e3.5 days is absurd and way way over dosed.

A man can increase fertility on HCG at 125 iu daily with no problem.

HCG is estrogenic and more importantly it aroamatases within the testes and AI are very poor in managing it or lowering it.

The symptoms you have are as a result of your elevated estrogen and you can't stay there long as there are health risks associated with it.

You need to get on a lower dose as soon as you can and/or find a new Doctor who understand Testosterone Therapy in men and get the right care.

Couldn't have said it better myself.

Please check out Defy Medical. They know what they're doing.
 
Couldn't have said it better myself.

Please check out Defy Medical. They know what they're doing.


I have a call in to another endo and will check out defy next week. I found a bottle of anastrozole the doc gave me when I was on clomid and I never used it. I'm thinking about taking .5mg now just to start to lower E2 and then check with new doc or defy next week, any thought on this? It's actually 1mg pills I was going to cut in half but maybe 1mg is okay? I know it's potent stuff so I don't want to over do it.
 
I have a call in to another endo and will check out defy next week. I found a bottle of anastrozole the doc gave me when I was on clomid and I never used it. I'm thinking about taking .5mg now just to start to lower E2 and then check with new doc or defy next week, any thought on this? It's actually 1mg pills I was going to cut in half but maybe 1mg is okay? I know it's potent stuff so I don't want to over do it.

No, 1mg is not ok...neither is .5mg. You're going to crash your E2 with that dose. Do you have any idea what you're doing? It sure doesn't seem like it.

Are you reading all the posts on this thread? ERO suggested .25mg twice a week as a starting dose. That's a reasonable starting dose of anastrozole. Please seek competent medical care (Defy), so you don't hurt yourself.
 
So i'm 38 years old, secondary and have had low test for at least a couple years. I decided about a year ago after a ton of reading on the forums that I wanted to get on trt but I need to get the wife pregnant first.


Last year the endo tried a clomid restart for a couple months and my TT went to 600 and E2 to 59 and I had more energy but libido and brain fog remained and after a few months off clomid my TT went back to about 250.

My last testosterone reading 6 weeks ago came back at TT 212, E was <5.1, LH was 6.1 and FSH was 3.2

5 Weeks ago the endo put me on a fertility dose of HCG at 3000iu e3.5d. and libido came up and a little improvement in energy but still have horribe brain fog. The doc wanted to wait 3 months before labs but I started to have more anxiety and a bit of acne so I got my own labs at privatemdlabs.com yesterday and the results have got me freaked out, TT 939 and E2(not the sensative) at 110-I know the sensative is better but it's a lot more $ and from what i've read the regular is usually within 10 or so of the sensative and I just wated and idea of where I was so I figured good enough.

I have a message in to the doc that I want to get arimidex but wanted some opinions for you guys.

What would be a good starting point on the dosage of the AI? I have heard sories of people tanking their e2 with and Ai so I dont want to go from one extreme to the other.

This high dose of HCG is only temporary and hopefully in a couple months ill be on testosterone every e3.5d with 250 iu HCG at the same time and try to keep test low enough to keep my ex between 20-30 to avoid an AI .

Ive done a study on myself with a lab draw and ordered BOTH tests from the same blood draw and the sensitive was HIGHER than the standard. You cannot use the standard test to base your care from.
 
I have a call in to another endo and will check out defy next week. I found a bottle of anastrozole the doc gave me when I was on clomid and I never used it. I'm thinking about taking .5mg now just to start to lower E2 and then check with new doc or defy next week, any thought on this? It's actually 1mg pills I was going to cut in half but maybe 1mg is okay? I know it's potent stuff so I don't want to over do it.

Are you reading the replies...people aren't going to keep talking if you're not listening.
 
Ive done a study on myself with a lab draw and ordered BOTH tests from the same blood draw and the sensitive was HIGHER than the standard. You cannot use the standard test to base your care from.


So are you saying the standard is completely worthless? You said the sensitive was higher for you but by how much? For example if my standard is 110 can the sensitive be say 15? If it was completely worthless i'm just a little surprised because my endo, erologist and my gp all use the standard, I don't doubt the sensitive is better but I can't afford $185 for labs vs $55 if I can get pretty close. I've done a lot of reading and the best I've found on a blood draw the same day was off by 10. Can anyone provide a link to anything that shows more than 10 that would be great. Keep in mind this is for a short term fertility dose of HCG and i'm not trying to dial in a long term trt protocol.

I will get the E2 sensitive at the 3 month follow up with the doc if I don't find a better doc or go to defy first.


I'm trying to to better that what the doc said by getting labs at 5 weeks instead of 3 months that he suggested.
 
No, 1mg is not ok...neither is .5mg. You're going to crash your E2 with that dose. Do you have any idea what you're doing? It sure doesn't seem like it.

Are you reading all the posts on this thread? ERO suggested .25mg twice a week as a starting dose. That's a reasonable starting dose of anastrozole. Please seek competent medical care (Defy), so you don't hurt yourself.

First if I knew exactly what I was doing I wouldn't be here asking for advice. Yes I saw Ero suggested .25 but my doc gave a script for 1mg twice a week and I just wanted a few more people to chime in before I went against my doc. If you believe the first thing someone says on a forum before your doc you may have real problems. There is a lot of info out there on HCG but not much on a fertility dose so thats why I asked for help.

I took .25 just now btw.
 
So are you saying the standard is completely worthless? You said the sensitive was higher for you but by how much? For example if my standard is 110 can the sensitive be say 15? If it was completely worthless i'm just a little surprised because my endo, erologist and my gp all use the standard, I don't doubt the sensitive is better but I can't afford $185 for labs vs $55 if I can get pretty close. I've done a lot of reading and the best I've found on a blood draw the same day was off by 10. Can anyone provide a link to anything that shows more than 10 that would be great. Keep in mind this is for a short term fertility dose of HCG and i'm not trying to dial in a long term trt protocol.

I will get the E2 sensitive at the 3 month follow up with the doc if I don't find a better doc or go to defy first.


I'm trying to to better that what the doc said by getting labs at 5 weeks instead of 3 months that he suggested.

As I noted above, my estradiol measured on the sensitive standard was half the value that the standard test reported. There is a very simple reason your doctors run the standard test - they don't know any better. That ought to cause you to walk away from them and not look back.
 
Last edited:
1 mg of Anastrozole twice a week is a huge overdose for 99% of guys on TRT and as CoastWatcher indicated, if he doesn't even know the proper E2 test to use, that in itself indicates he is not the right Doc for TRT success.
 
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So are you saying the standard is completely worthless? You said the sensitive was higher for you but by how much? For example if my standard is 110 can the sensitive be say 15? If it was completely worthless i'm just a little surprised because my endo, erologist and my gp all use the standard, I don't doubt the sensitive is better but I can't afford $185 for labs vs $55 if I can get pretty close. I've done a lot of reading and the best I've found on a blood draw the same day was off by 10. Can anyone provide a link to anything that shows more than 10 that would be great. Keep in mind this is for a short term fertility dose of HCG and i'm not trying to dial in a long term trt protocol.

I will get the E2 sensitive at the 3 month follow up with the doc if I don't find a better doc or go to defy first.


I'm trying to to better that what the doc said by getting labs at 5 weeks instead of 3 months that he suggested.

The test is the wrong test, it's that simple. It's for females, not males, and is thus, the wrong test. And those "Dr's", are using the wrong test, and it can't be extrapolated, accurately, for male use. It can't be made more clear.
 
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