10 Weeks in & Not Feeling as Good as Hoped

[Harpua]

Hi Guys. 44 year old male with decades of lower T (200-400) - finally started TRT in February.

I am not feeling great several weeks into TRT. Appointment with clinic in a month but looking for any opinions.

Protocol -
testosterone cypionate 200 mg/mL - .4 ml 2x week
HCG 3000 75iu 2 x week for 4 weeks - off 1 week
Anastrozole .75 mg 1x week

Labs Prior to Starting TRT Feb 2017:
Total T - 211
Free T - 6.12
E - 13.2
SHBG - 36.2
TSH - 1.7

May (9 weeks in)
Total T 1289
Free T- 22.2
E - 34.5
SHBG - 27.6
TSH - 1.9
DHEA Sulfate - 110

On paper, from what I've read, numbers look fine but I'm easily and frequently agitated, tearing up at during parts of movies not meant to get teary at, and libido/erections are weak after being good for weeks 1-4ish. Getting sleep, not depressed but not feeling "great." Had night sweats two nights this week.

Before treatment, I was experiencing almost a year of unexplained depression symptoms (which quickly resolved after raising T and have not returned) and low libido. I really don't like being so irritable.

Any thoughts? Thanks.

 

[Harpua]

Dhea

While waiting for someone to chime in, been reading more about DHEA levels. 110 seems a bit low. I haven't been supplementing with any DHEA as I don't want E to get too high but wondering if DHEA is a culprit....

Hi Guys. 44 year old male with decades of lower T (200-400) - finally started TRT in February.

I am not feeling great several weeks into TRT. Appointment with clinic in a month but looking for any opinions.

Protocol -
testosterone cypionate 200 mg/mL - .4 ml 2x week
HCG 3000 75iu 2 x week for 4 weeks - off 1 week
Anastrozole .75 mg 1x week

Labs Prior to Starting TRT Feb 2017:
Total T - 211
Free T - 6.12
E - 13.2
SHBG - 36.2
TSH - 1.7

May (9 weeks in)
Total T 1289
Free T- 22.2
E - 34.5
SHBG - 27.6
TSH - 1.9
DHEA Sulfate - 110

On paper, from what I've read, numbers look fine but I'm easily and frequently agitated, tearing up at during parts of movies not meant to get teary at, and libido/erections are weak after being good for weeks 1-4ish. Getting sleep, not depressed but not feeling "great." Had night sweats two nights this week.

Before treatment, I was experiencing almost a year of unexplained depression symptoms (which quickly resolved after raising T and have not returned) and low libido. I really don't like being so irritable.

Any thoughts? Thanks.

 

[Zooka15]

Do you have the range for your E2 labs...Also what Type of was used Regular or sensitive (per quest diagnostics Ultra sensitive). also the range is needed for DHEA

 

[CoastWatcher]

Hi Guys. 44 year old male with decades of lower T (200-400) - finally started TRT in February.

I am not feeling great several weeks into TRT. Appointment with clinic in a month but looking for any opinions.

Protocol -
testosterone cypionate 200 mg/mL - .4 ml 2x week
HCG 3000 75iu 2 x week for 4 weeks - off 1 week
Anastrozole .75 mg 1x week

Labs Prior to Starting TRT Feb 2017:
Total T - 211
Free T - 6.12
E - 13.2
SHBG - 36.2
TSH - 1.7

May (9 weeks in)
Total T 1289
Free T- 22.2
E - 34.5
SHBG - 27.6
TSH - 1.9
DHEA Sulfate - 110

On paper, from what I've read, numbers look fine but I'm easily and frequently agitated, tearing up at during parts of movies not meant to get teary at, and libido/erections are weak after being good for weeks 1-4ish. Getting sleep, not depressed but not feeling "great." Had night sweats two nights this week.

Before treatment, I was experiencing almost a year of unexplained depression symptoms (which quickly resolved after raising T and have not returned) and low libido. I really don't like being so irritable.

Any thoughts? Thanks.

Can you provide ranges for all of these tests?

 

[Harpua]

Can you provide ranges for all of these tests?

Labs Prior to Starting TRT Feb 2017:
Total T - 211 ng/dL

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(348-1197)
Free T - 6.12 ng/dl (4.46-17.1)
E - 13.2 pg/mL

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(7.6-42.6)
SHBG - 36.2 nmol/L (16.5-55.9)
TSH - 1.7 mIU/L (.25-4.94)

May (9 weeks in)
Total T 1289 ng/dL

​

​

​

(348-1197)
Free T- 22.2 ng/dl (6.8-21.5)
E (sensitive)- 34.5 pg/ml (8.0-35.0)
SHBG - 27.6 nmol/L (16.5-55.9)
TSH - 1.9 mIU/L (.25-4.94)
DHEA Sulfate - 110 ug/DL (102.6-416.3)

 

[Harpua]

Do you have the range for your E2 labs...Also what Type of was used Regular or sensitive (per quest diagnostics Ultra sensitive). also the range is needed for DHEA

Sorry--first was regular and 2nd result was sensitive. Ranges added....

Thanks.