serotonin

  1. Seagal

    Serotonin SSRI appetite regulation and beyond

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10408233/
  2. J

    Reassessing Serotonin

    From Jay Feldman
  3. T

    The serotonin theory of depression: a systematic umbrella review of the evidence (20 July 2022)

    It is often assumed that the effects of antidepressants demonstrate that depression must be at least partially caused by a brain-based chemical abnormality, and that the apparent efficacy of SSRIs shows that serotonin is implicated. Other explanations for the effects of antidepressants have been...
  4. G

    Serotonergic system fix

    I was listening to a podcast with Mark Bell and they discussed how nandrolone can have permanent effects in down regulating the serotonergic system particularly in younger men. Was wondering what could be done to mitigate these effects if anybody has any experience on the topic.
  5. S

    TRT and Serotonin

    I'm curious to know whether or not long-term HPTA shutdown, or some other mechanism from long-term TRT, has any effect on brain serotonin levels, serotonin transmitters, or the brain's ability to uptake serotonin. Anyone have any insight here? @Mountain Man ?
  6. S

    TRT and Neurotransmitter Balance

    What effects, if any, does TRT have on neurotransmitters, particularly on serotonin? I know that in the initial stages of TRT, there is a pronounced effect on dopamine - I have been told that this is what causes the "honeymoon" that many guys experience. Are there neurotransmitter imbalances...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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