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  1. S

    Excess niacin causes blood vessel inflammation and cardiovascular disease

    They are finally realizing that anything promoting blood vessel inflammation, in this case excess niacin metabolites, can lead to cardiovascular disease. It's not the cholesterol.
  2. M


    Anyone notice impact on fasting and post-prandial glucose levels and a1c from taking high-dose ER niacin to manage lipids? I was on 1.5g per day and increased to 2g per day and now I'm noticing glucose levels about 10 points higher. Wondering if this will subside over time. I know some are...
  3. W

    Histamine, Low Libido and ED

    Libido and ED as bad as they have ever been. Tried Prog at night per Dr. Saya's recommendation and no help at all. In the last month, I have weaned off HC after being on it for years and I feel a bit calmer without it, but the sexual dept is as stated. 25 years of this. Close to throwing in the...
  4. Kaus Klinski

    Niacin and lipolysis - does it inhibit/impair fat loss?

    Hi, I'm currently thinking about adding some niacin to my supplement stack (about 250-500 mg/day) for it's beneficial effects on the lipid profile, mainly, I'd like to up my HDL a little. But I'm concerned about it's potent antilipolytic effects (which is the actual mechanism behind it's...
  5. G

    High-Dose Niacin: A Cautionary Tale

    High-dose Niacin was generally considered very beneficial before about 2010 but then fell into a bit of disfavor without much credible change in the science. I have been watching the evidence for a long time and it seems incomplete but generally positive. I have tried niacin on and off without...
  6. H

    Niacin (nicotinic acid)

    Is it safe to take nicotinic acid 500mg twice a day? I am not talking about the non flush stuff. I started 500mg daily to try to increase my HDL but heard that higher dosages might be necessary. Anyone here taking nicotinic acid and any elevated liver enzimes or HCT?
  7. Nelson Vergel

    Decreased HDL Caused by Higher Dose TRT

    Higher dose testosterone can decrease HDL. Click here for background information: Why does testosterone therapy decrease HDL cholesterol in some men? HDL (High Density Lipoprotein cholesterol) particles are sometimes referred to as "good cholesterol" because they can transport fat molecules...
  8. JWSimpkins

    Niacin and Cholesterol

    Hey guys, Has anyone had success lowering LDL cholesterol with high dose Niacin?
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