metformin

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  1. Nelson Vergel

    Is Metformin a Miracle Drug ? : Nelson Vergel Explains

    Jay Campbell invited me to present a review of relevant data on the use of Metformin in men with and without diabetes. I hope you enjoy the work I put into explaining the data to clarify the myths and facts about this old drug that is creating so much interest in the anti-aging world.
  2. Nelson Vergel

    Is Metformin a Miracle Drug ? : Lecture

    Jay Campbell invited me to present a review of relevant data on the use of Metformin in men with and without diabetes. I hope you enjoy the work I put into explaining the data to clarify the myths and facts about this old drug that is creating so much interest in the anti-aging world.
  3. P

    Can Metformin lower Free and total T levels?

    According to Life Extension, it may. http://www.lifeextension.com/Magazine/2017/4/Metformin-Slashes-Cancer-Risks/Page-01 Just got my T levels dialed in at 1076, the last thing I want is something to lower them, opinions?
  4. J

    First Follow-Up Blood Work Since Starting TRT

    I got my first follow-up blood work since starting TRT on March 15th and would appreciate any thoughts/insights. To get an idea of where I started see posts #43, #44, and #61 in: https://www.excelmale.com/forum/showthread.php?7844-Went-to-Urologist-Today-Your-Thoughts-Please/page3 My protocol...
  5. Nelson Vergel

    Metformin may work by changing gut bacteria makeup

    During the study period, the collection of gut bacteria changed much more dramatically in those taking metformin. In particular, the drug seemed to encourage the growth of strains of bacteria called Akkermansia and Bifidobacterium. Lab experiments revealed that both types also grew faster in the...
  6. J

    Constipation - Is it TRT - Metformin

    About 5 weeks ago I started taking T-Cyp, Metformin, and once per week 0.25 mg of an AI. Prior to taking any of those medications I always had regular (at least once per day) bowel movements. I've noticed since starting TRT, etc. that bowel movements are irregular, a little more difficult, and...
  7. Nelson Vergel

    Will Metformin Become the First Anti-Aging Drug?

    A committed group of scientists is seeking to validate metformin as the first-ever anti-aging medication.1,2 In this day of staggering drug prices, metformin is available as a low-cost generic. One mechanism by which metformin works is by activating AMPK, an enzyme inside cells that lowers...
  8. Nelson Vergel

    Metformin reduces exhaustion of immune cells in HIV+ people on HIV meds

    METFORMIN REDUCES T-CELL EXHAUSTION IN A CLINICAL TRIAL OF HIV-INFECTED ADULTS ON ART Author(s): Glen Chew1, Dominic Chow1, Scott A. Souza1, Lindsay Kohorn1, Richard M. Watanabe2, Ivo Sah Bandar1, Eun-Young Park1, Mary Margaret Byron1, Lishomwa C. Ndhlovu1, Cecilia Shikuma1 1Univ of Hawaii...
  9. A

    Metformin: Are you taking it and what has your experience been?

    I have read a lot lately about people taking Metformin even though they are not diabetic/pre-diabetic for health/anti-aging reasons. As I'm sure you are all aware, it is purported to have beneficial effects similar to calorie restriction as well as the many other health claims. It is also cited...
  10. T

    Metformin and Testosterone

    I know several people that take this. Has this been a help with metabolic syndrome? Should I take the ER or immediate? I do not have diabetes but have high blood pressure, (132/81 avg) high triglycerides (150-170 dosing 4.8 grams fish oil), high cholesterol (220), non hdl and hdl slightly out...
  11. Nelson Vergel

    Water Retention Caused by Testosterone May Have Nothing to Do with Estradiol

    I get a lot of emails from men on testosterone replacement therapy (and/or HCG) that feel they have water retention (some with ankle swelling) and they are puzzled that their estradiol is low or below 35 micrograms/ml. They may have tried anastrozole treatment without any success in decreasing...
  12. Nelson Vergel

    Dr Lynese Lawson: Beyond Testosterone Lecture

    PART 1 Nelson: Hello everybody, Nelson Vergel here with ExcelMale.com. I'm very happy to have Dr. Lawson from the Washington DC area. She's a long term friend of Excel Male and the work we do with men's health and testosterone replacement therapy, among other things. Dr. Lawson is the founder...
  13. Nelson Vergel

    Trying to reduce internal belly fat : Metformin plus growth hormone releasing hormone

    Trying to reduce internal belly fat Sep 28, 2016 Hi Nelson, I am just about to start Egrifa and I am wondering if I should also go on Metformin? I am not diabetic. I have extremely thin legs and arms and then this hard internal belly fat. Do you think I would get better belly fat reduction with...
  14. Nelson Vergel

    Metformin improves semen and testosterone in men with metabolic syndrome

    Metformin improves semen characteristics of oligo-terato-asthenozoospermic men with metabolic syndrome Fertility and Sterility Volume 95, Issue 6, May 2011, Pages 2150–2152 Forty-five patients (age range: 26 to 44 years) were evaluated. Five patients experienced mild side effects such...
  15. Nelson Vergel

    Effect of metformin on thyroid stimulating hormone and thyroid volume in patients with prediabetes

    Effect of metformin on thyroid stimulating hormone and thyroid volume in patients with prediabetes: A randomized placebo-controlled clinical trial. Journal of Research in Medical Sciences. Nov2014, Vol. 19 Issue 11, p1019-1026. 8p. Abstract: Background: The people with prediabetes have...
  16. Nelson Vergel

    Testosterone Replacement Enhances the Effects of Metformin on Lipids and Inflammation

    Exp Clin Endocrinol Diabetes 2015; 123(10): 608-613 The Effect of Metformin and Metformin-Testosterone Combination on Cardiometabolic Risk Factors in Men with Late-onset Hypogonadism and Impaired Glucose Tolerance Abstract No previous study has investigated the effect of metformin...
  17. Vince

    where to buy metformin without a script

    I have a script from my preventive doctor, who is a firm belever in the benefits metformin. My girlfriend's doctor is not, so for her I'm looking for the best place to get metformin without a script.
  18. Nelson Vergel

    A new study explores anti-aging properties of metformin

    Research has found that metformin targets the chemicals produced by age-related senescent cells—normal cells that stop dividing and produce toxic substances damaging to the cells around them, said James Kirkland, director of the Robert and Arlene Kogod Center on Aging at the Mayo Clinic in...
  19. Nelson Vergel

    How to decrease HIV related belly fat accumulation

    Decreasing HIV Related Belly Fat Accumulation In the mid-90s with the advent of the first antiretroviral (AVR) drug combination therapies, Kaposi’s sarcoma (KS) lesions and lipodystrophy (wasting away of body fat) rapidly faded from public consciousness as signs of HIV infection. Only to be...
  20. P

    Can Metformin help me lose weight?

    Hi everyone, My name is Paul. I am a 48 year old male, 120kg (264 pounds) HIV+ since 2003. HIV is fine and undetectable. My endocrine system is another thing altogether. My current regimen is as follows: 2ml depo testosterone weekly 1 x 25mg Aromasin every 6 days. (used to be every 3 days but...
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