Will Metformin Become the First Anti-Aging Drug?

[Nelson Vergel]

A committed group of scientists is seeking to validate metformin as the first-ever anti-aging medication.1,2

In this day of staggering drug prices, metformin is available as a low-cost generic.

One mechanism by which metformin works is by activating AMPK, an enzyme inside cells that lowers blood sugar by promoting energy utilization.

Activating AMPK has broad-ranging effects that extend far beyond blood sugar control. Studies show that boosting AMPK activity can prevent—and even reverse—the life-shortening effects of aging, such as cardiovascular disease, diabetes, neurodegenerative diseases, cancer, and more.3

In this article, we’ll review data that persuaded the FDA to allow metformin to be studied in humans as the first anti-aging drug.1

http://www.lifeextension.com/Magazine/2017/4/Metformin-Slashes-Cancer-Risks/Page-01

 

[Nelson Vergel]

A new study explores anti-aging properties of metformin

https://www.excelmale.com/forum/showthread.php?3435...metformin

Research has found that metformin targets the chemicals produced by age- related senescent cells—normal cells that stop dividing and .

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Metformin

https://www.excelmale.com/tags.php?tag=metformin

Results 1 - 9 of 9 ... Metformin reduces exhaustion of immune cells in HIV+ people on HIV meds ... Metformin: Are you taking it and what has your exper

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Can Metformin help me lose weight?

https://www.excelmale.com/forum/showthread.php?1950...Metformin...

Hi everyone, My name is Paul. I am a 48 year old male, 120kg (264 pounds) HIV+ since 2003. HIV is fine and undetectable.

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Testosterone Replacement Enhances the Effects of Metformin on ...

https://www.excelmale.com/archive/index.php/t-5714.html

Exp Clin Endocrinol Diabetes 2015; 123(10): 608-613 The Effect of Metformin and Metformin-Testosterone Combination on Cardiometabolic ...

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where to buy metformin without a script

https://www.excelmale.com/forum/showthread.php?4002...metformin...a...

I have a script from my preventive doctor, who is a firm belever in the benefits metformin. My girlfriend's doctor is not, so for her I'm looking for ...

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Metformin-interesting read

https://www.excelmale.com/forum/showthread.php?5733-Metformin...read

But very interesting read! http://www.inquisitr.com/2599362/diabetes-drug- metformin-could-increase-human-lifespan-to-120-years/

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[PedroZuñiga]

Thanks for sharing this content

 

[Sean Mosher]

Very good stuff!

 

[Holden]

Thanks Nelson! Great articles!

So given these and other recent studies and articles, curious if your opinion has changed since June 2015 where you posted, "I would only take metformin if I am fat, have glucose intolerance or insulin resistance. It can lower your T and B vitamins (if you are on TRT and taking vitamins this is a moot subject). It can cause gut distress at doses higher than 1000 mg per day. It can also lower appetite."

Here's my situation:
I'm not fat, but prob 10lbs overweight, 6'1', 195lbs
my A1C is not bad 5.5,
Glucose 90 (65-99)
Triglycerides 98
Total Chol 172
HDL 43
LDL 109
VLDL 20
my cardio vascular system seems fine ( CT scan with contrast, 0.0 calcium, no stenosis ),
I am 50 yrs old so starting to consider best approaches for avoiding cancer, and longer term Alzheimers. I am a Defy patient and working through the testosterone situation.

Appreciate your latest views on metformin thanks!

-H