injection site reaction

  1. S

    Did I hit a nerve?

    I just started injecting a couple weeks ago. The first two went great. I did my third on saturday and thought that one also went great but yesterday, two days after the injection I have terrible pain in my thigh. Kept me up most of the night, so I guess I hit a nerve and had a delayed reaction...
  2. aaghabegian

    Site Reaction

    Hello everyone, I’m honored to be on this site and thank you Mr. Vergel for all the education through your excellent books. I am a Physician Assistant practicing in CA and have been on TRT for about 11 years. My treatments began 11 years ago with a few IM injections that I could not tolerate due...
  3. M

    Firm, painful knot at injection site

    I've been on TRT for 10 years. I inject 0.2 ml (40mg) of testosterone cypionate twice per week. A few months ago I started injecting HCG (200mg) at the same time. I first draw the testosterone into the syringe, and then draw the HCG into the same syringe. I use a new needle when drawing each...
  4. J

    Skin Darkening at Injection Site

    I inject in the same general areas on my abdomen twice a week. Test on one side, hCG on the other side. I noticed my skin there is darkening (I'm a brown man). Is this hyperpigmentation or something else? Would hydroquinone work?
  5. D

    Kinda nasty bruise/hardness after injection...

    So I had my morning subq love handle injection 4 days ago and it didn't go very smoothly. Syringe was sticky and may have pressed too fast, and was more painful than normal. Decent bleed afterward but I just applied pressure and did not even need to bandage it to get it to stop. Well, as of...
  6. M

    T-cyp from one pharmacy burns, other does not?

    Started TRT 3 months ago. I'm on 160mg T-cyp weekly (divided into 2 doses of 80mg). For the past 3 months, I've been injecting subQ with Tcyp from Olympia pharmacy. Yesterday, I received my first subQ injection from Tcyp from Empower pharmacy. The Tcyp from Olympia always caused a burning...
  7. keithc2485

    Pain and swelling after needle stick in R thigh .. concerned

    Hey guys. So I've been doing self-injections for 5 years and I'm pretty good at them. but today I was distracted I guess, on speakerphone etc. Anyway I was doing my testosterone injection in my right upper thigh I think I went a little too middle and when I injected the needle my whole leg...
  8. Vin

    Muscle twinge when injecting into deltoid ??

    Hello all, I did a search to see if anyone else has had an issue when injecting into into the deltoid.. been on trt for 2 years.. started with glut injections but went to deltoids as it was easy and with a smaller gauge don’t feel it.. So I’ve had this happen more often recently .. when...
  9. S

    injected subq to high over love handle and blood squirted out after pulling out needle ...

    only bled for a few secs , ran down my side ....should I be worried about not getting my correct dose ?
  10. C

    Injection Site Issue/Question

    Hey Guys! Something happened to me today that has never happened before , and I like to get some advice/theory on what I did wrong. I inject 50 mg of Test Cyp every 3 days. I use an insulin syringe and usually inject into left shoulder because I’m right handed(have done my right shoulder a few...
  11. M

    Injection site reaction

    I have been having a few bad injection site reactions and looking for ideas on how to mitigate the symptoms. I've read through many of the threads here, but wondering if my particular symptoms will sound familiar to anyone and what the fix was. Every injection, using 1/2" 27g on delts, dorsal...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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