bremelanotide

  1. S

    My PT141 Arrived Today - Is 20 Units Considered Too Much?

    Hi guys.. My pt141 arrived today with instructions to keep it refrigerated. I never tried it before in my life. Dosage of injection is 20 units. I assume 20 units is whats marked as '20' on the syringe, correct? If thats the case, is that considered too much for a 1st time user?
  2. C

    A different dosing strategy with bremelanotide (PT-141) yields dramatically better results

    TL;DR: It may be possible to improve results with bremelanotide by taking multiple daily micro-doses. Like many, I have experimented with bremelanotide at the recommended doses, which range from a few hundred micrograms up to a couple milligrams in one subcutaneous injection. And also like...
  3. S

    Why so little info on Bremelanotide (PT-141-Vyleesi)?

    There is an astonishing lack of talk on here about a drug which attempts to address something that we talk about all the time and have zero tools to fix - libido. Now that we have multiple phase three studies to review on Pubmed and an FDA approved product perhaps we need to start gathering...
  4. G

    PT-141 officially FDA approved (for women)

    FDA approves new treatment for hypoactive sexual desire disorder in premenopausal women PT-141 AKA Bremelanotide AKA Vyleesi approved. This should open up a whole new focus on the melanocortin system and allow for crowdsourcing the best dosing/timing. It seems something good is happening in...
  5. Nelson Vergel

    Bremelanotide (Vyleesi) for Female Sexual Disorder

    Rekynda (bremelanotide), an investigational product, is thought to possess a novel mechanism of action, activating endogenous melanocortin pathways involved in sexual desire and response. The two Phase 3 studies for HSDD in pre-menopausal women consisted of double-blind placebo-controlled...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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