1. #1

    negatives and risks of not backfilling the pathway [DHEA, PREG]

    What are the negatives to not backfilling the pathways and not taking DHEA and pregnenolone on trt? Any long term risk doing so?

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  3. #2
    Backfilling is overhyped, IMHO. DHEA more than Preg, can be not well tolerated in a lot of guys, aromatases easily, etc. But like all of this some love DHEA, some love Preg, and some like me avoid it entirely. There are no negatives to not supplementing...it's like one of these things that (IMHO) it's treating a number on a lab page vs is it really necessary to do it.

  4. #3
    Moderator Vince's Avatar
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    Feb 2014
    Milwaukee, WI
    I know we have many threads on back filling the pathways, but many members cannot deal with the HCG and DHEA because of estrogen levels or sleep issues. I think back filling is a very individual thing, I do supplement with 25 mg of DHEA daily and 500 IU of HCG every 3 1/2 days. But that's me.

    I am not a medical practitioner. Any suggestions I provide are not medical recommendations and are just my opinions. Please consult with your physician on any matters concerning your health.

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