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    Ferritin vs hematocrit, blood donation

    Dr Rudy Eberwein explains how to Manage Iron Overload: Causes, Supplements, Treatment
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    Supra physiological FT

    Dr Keith Nichols explains Why You May Need Supraphysiological Testosterone Levels.
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    Association Between Sex Steroid Hormones and Hematocrit in a Nationally Representative Sample of Men

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774012/ We did not have a hypothesis about the association between estradiol and hematocrit because to our knowledge, there is no direct mechanistic link between estradiol and erythropoiesis. Yet, we found that men with higher concentrations of...
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    Effect of Exercise for Depression: Systematic Review of Randomised Controlled Trials

    Abstract Objective To identify the optimal dose and modality of exercise for treating major depressive disorder, compared with psychotherapy, antidepressants, and control conditions. Design Systematic review and network meta-analysis. Methods Screening, data extraction, coding, and risk of...
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    Bioavailable testosterone is associated with symptoms of depression in adult men

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557700/ Results Mean testosterone, sex hormone-binding globulin, and luteinizing hormone levels were significantly higher in the depressive symptom group than in the non-depressed group. The mean calculated free serum testosterone level and free...
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    Functional neuronal circuits emerge in the absence of developmental activity

    https://www.nature.com/articles/s41467-023-44681-2 https://www.psypost.org/neuroscience-harvard-scientists-just-revealed-a-remarkable-fact-about-brain-development/ “In the age-old question of nature versus nurture, we land decisively on the side of nature,” Barabási told PsyPost. “We challenge...
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    Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk

    https://www.nature.com/articles/s42255-024-00984-2 High protein intake is common in western societies and is often promoted as part of a healthy lifestyle; however, amino-acid-mediated mammalian target of rapamycin (mTOR) signalling in macrophages has been implicated in the pathogenesis of...
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    Sex Differences in Association of Physical Activity With All-Cause and Cardiovascular Mortality

    https://www.sciencedirect.com/science/article/pii/S0735109723083134 During 4,911,178 person-years of follow-up, there were 39,935 all-cause deaths including 11,670 cardiovascular deaths. Regular leisure-time physical activity compared with inactivity was associated with 24% (HR: 0.76; 95% CI...
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    Testosterone and prosocial behavior

    https://www.nature.com/articles/s41386-023-01570-y
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    DHEA supplementation for hypothyroidism

    https://link.springer.com/article/10.1007/s11096-020-01207-w DHEA supplementation may exert a beneficial effect on thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in men with autoimmune thyroiditis and subclinical hypothyroidism.
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    DHEA -- Age Trends in the Level of Serum Testosterone and Other Hormones in Middle-Aged Men

    https://academic.oup.com/jcem/article/87/2/589/2846777 Dehydroepiandrosterone, dehydroepiandrosterone sulfate, cortisol, and estrone showed significant longitudinal declines, whereas dihydrotestosterone, pituitary gonadotropins, and PRL rose longitudinally.
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    Relation of Testosterone, Dihydrotestosterone, and Estradiol With Changes in Outcomes Measures in the Testosterone Trials

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9016457/ "These analyses were not prespecified and need confirmation in additional studies of other datasets. Our models were modestly predictive, with r-squared values ranging from 0.16 for HDL cholesterol to 0.27 for vBMD, indicating that there...
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