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I think I edited the post after you replied, but basically fatty liver (non-alcoholic that is) is caused by insulin resistance. High blood sugar and insulin resistance damage your endothelial walls (and kill your erections). I invite you to research this topic heavily. Evaluation of endothelial...

Yeah, a FBG is better than nothing, but not ideal to see where you fall on the metabolic scale. Get a A1C, do a OGTT or better yet do an insulin survey with your OGTT. That's good on the trigs. Also test your liver with AST, ALT, and GGT. Still, I think if you have onset fatty liver and are...

Yes, you're low normal, but I would still say low. And also we can see that you have fatty liver too so the correlation is there. You're likely insulin resistant. I wouldn't worry about total cholesterol so much as I would high trigs and low HDL. What is your trig value? HDL? High trigs, low...

Low SHBG is strongly associated with insulin resistance/metabolic syndrome. Erections are far more than hormones. The health of your endothelium and proper vasodilation is critical for erections (even PDE5 inhibitors can't overcome these). What is your A1C? GGT? Have you done an insulin survey...

You can def try and stack them. The yohimbine can bring your bp back up a bit while still blocking the receptors. In my case yohimbine boosted my libido but would give me tight sac and quickly fading erections because it raises norepinephrine (too much flight...). Ultimate Adrenergic Control of...

Sluggish, lack of motivation, would get lightheaded if I stood up too fast, negative effects on exercise, etc. I could take and tolerate it but didn't feel like it was addressing any roots causes of my issues. The hangs it gives are pretty awesome tho!

Yes, this is exactly why it works. It works for me in this same manner. I've always been too norepinephrine dominate and any drug, like Doxazosin, improves erection quality (in terms of maintaining them in my case). However the side effects are not tolerable for me. I also tried Atomoxetine...

Some people are not able to convert NAC to glutathione. NAC is good to get to 'baseline' but if your baseline isn't naturally high you won't achieve high levels of glutathione. It also seems to be limited by how much glycine is present in the body...

Yes, Met absolutely controls the level to which glucose rises if I take 500mg with a meal. I have a meter and can verify. Even at 500mg a day my blood sugar as far as I can tell doesn't go above 115 or so post meal and often not above 100. I've eaten meals with met and an hour later my BS is...

Just an update - I lowered the dose to 500mg total per day and now have normal energy levels. I think I'm just sensitive to this drug. At 500mg a day I get the benefits but have normal levels of energy. Pretty stoked on that. I might even try taking 500mg every other day - basically taper down...

atlien2488 - Your SHBG is low. Have you ever been tested for fatty liver or done a insulin/OGTT Kraft survey? Guys with low SHBG might have insulin resistance or be norepinephrine dominate (neurotransmitter imbalance) and this is causing vasoconstriction and endothelial dysfunction (or low SHBG...

These association/observational studies are voodoo science. I wish they would just stop. These are not experiments. The risk ratio are so low that in other sciences they would be dismissed. The smoking risk/ratio was 10x or more, this is 1.18. Not only that but these are food questionnaires...

I started Met at 500mg 2x instant release about 6 weeks ago. At first it was amazing. Belly fat melted off, no bloating, I felt more relaxed and calm than normal, my flaccid hangs were bigger and relaxed, and had much improved erections (it helped more than Cialis every did and improved the...

Thanks guys. I might try a simple oil or PG solution first. I have to experiment and see what the mg/ml solubility is.

Like many of you I've been following the latest discussions about testosterone cream (esp interested in combing injections and creams) and interested in giving it a go. I'm not in the USA at the moment and unable to get a compounded cream where I live, but I can certainly get the test powder to...

Thank you so much for taking the time to answer my question! I'm doing 250IU EO2 at the same time as my T. Is that too much? It seems like you feel anything under 1000iu per week of HCG shouldn't cause too many sides, like high E2, yet still does its magic. Also, I dose my AI same day, so all...

Hi Dr Saya - This is great study. Thanks so much for sharing this. Do you feel those with lower SHBG (mine is 23) would do better on lower amounts of HCG because of greater aromatization concerns? Does SHBG play into how your prescribe HCG at all? Also, do you feel if someone is doing test...

Why not simply try to get in the mid 20s and see how you feel? Some guys are very sensitive to E2 and your baseline was bottom range. At 35 you're almost 3x your baseline. That's a big change in E2. Some guys seem to do best 15-25. Some guys might feel great at 35 and others may not. I look at...

Thanks for sharing your story, Vince. Do you manage E2 at the moment with an AI? If so, what's your dosing? I do EOD injections too so I'm curious.

From what I've seen on the boards most recommend that low SHBG guys do more frequent dosing. Can you provide a link or study that sites what you're suggesting? I'm low SHBG (17) and interested in this topic. I'm not doubting you, just curious because your position doesn't lineup with my...

Thanks for the feedback guys. :o

I'm 38, on TRT, 100mg a week, EOD subq, no HCG, .125mg to .25mg AI 2x a week, and in shape and lean. No other meds and I did not get a reverse T3.

Hey Guys, I have some labs values for Thyroid that fall within the reference range but I have symptoms (have always had these) like: dry skin pulse below 70 sometimes morning basal temperature below 97.8 oF or 36.5 oC cold hands or feet when others feel fine constipation (if I don't consume...

Hey guys - got my blood work back and my DHEA is low. I'm considering supplementation. Dr. John on Super Human Radio says he has guys take 50mg a day, once in the morning and then again 12 hours later. He didn't mention which type of DHEA but it seems like capsules. There seems to be some...

Thanks. These are very good prices. For the $25 is that monthly? That's covering T, HCG and AI?

if you don't mind, could you break down the average monthly with Defy? Let's say 100mg, 500iu hcg, 1mg arimidex a week type protocol. What was your setup cost to get going with them?

Alex, because I'm considering using Arimidex this is question I wanted answered as well. I think this question/answer from All Things Male might help you: "Jimstigator said: ↑Estrogen... my nemesis. I now get testosterone and SHBG. Estrogen is the same? For the sake of my...

You might be right, but I've been using them for 6 tests straight and my baseline prior to TRT was 26 with these tests. Are they not consistent? I don't care if they read high, I only care if they read high consistently. I can tell you I felt better sexually when I had 2 readings done at both...

Well this is non-sensitive test too, but that's all I got. Also, I've only used these tests so if they are constant then I should be able to rely on it. I most certainly had a better sex life at 26 then I do at 54 or 72. I know that. According the online Free T calculator that was recommend on...

Yeah that's what I was thinking. I'm looking at the pill and I don't see how I can get this into 1/8s. I just got my test results back and I'm: TT - 792 E2 - 54 SHBG - 17 No HCG or anything else for the last month. My last reading, a month ago was 72. I think it dropped because of the lack...

Was this directed at my question regarding using Arimidex?