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Gotcha thanks for explaining.

Right I see what you mean about the accuracy. My question is what do we do with the Tru T number. Presumably we are all dosing to a dose based on a combination of factors: 1) doctor's clinical experience (I'm with defy) 2) a level that ameliorates symptoms 3) a level that has minimal to no...

Hi All - Quick question. To build on DragonBits point made about the ranges. While I agree that having the most accurate diagnostic testing is always the best case, my question is this: If the magnitude of the error in the direct Free Testosterone test is roughly the same in all (Big if and...

Great thanks Pringle and Big.

Hi all - I accidentally left my mixed Hcg solution on the bathroom sink for 24 hours or so at room temperature. I've since put it in the fridge. Is it still good to use or will it have lost its potency? Thanks

The liothyronine from empower can be compounded as sustained release. I'd imagine it's cheaper than cytomel because it's from a compounding pharmacy. The hydrocortisone is to boost my cortisol levels which were on the lower side.

Vince reading your first two links it seems like the concerns brought up are due to taking too much t3 and going hyper. Is that fair to say? Would you expect that a T3 only protocol that targets mid upper reference range would run the same risks? FWIW, I'm currently taking sustained release...

Curious what everyone's thoughts are on high intensity training. There's a lot of research coming out that what matters most is intensity of effort rather than load. Ie training to failure with 50%,75%, or 90% of 1RM all achieve the same thing for the most part. Additionally the research is...

Has anyone spent any time looking into Vasper? The basic principle is that they use compression and cold technology to do high intensity exercise and the cooling allows a larger than normal lactic acid build up which signals to the brain to release a lot of anabolic hormones. Apparently it's...

Thanks all for the feed back. Is it fair to say in the absence of any difference symptoms wise one should revert to the lowest dose possible?

S1W ya didn't notice any difference at all and have opted for the lower dosage for the time. VC correct I haven't had any E2 symptoms whatsoever on either dosage.

What are people aiming for in Free T? I've seen people with troughs well over 1.5-2x the normal range which would place them even higher on peaks. I've had the below labs with no symptoms of high E2 and no AI and no difference really in the way I feel. Is there any benefit to the higher or lower...

Great thanks

Hi all I plan on traveling internationally to Spain and Portugal and was wondering what, if anything, I'd need to do in order to bring my testosterone cypionate, Hcg, and hydrocortisone. Thanks

If you don't mind Sakuraba can you give a little more detail as to what you did?

Great thanks Jones.

Jones - What have you seen done to restore the adrenals while concurrently taking low dose hydrocortisone.

I'm not sure if I'm following the logic here Dr. Crisler. It was my understanding that you were a proponent of going low and slow on testosterone dosage. Having trialed from say 75mg up to 200mg the patient titrates up until symptoms are relieved and finds an appropriate dosage. The option to...

Based on the recommendation here I'm low at 3 points Recommended Labwork - Stop The Thyroid Madness The idea is to see if the hydrocortisone helps as a diagnostic tool then look for ways of restoring the adrenals if possible.

Has anyone who's used hydrocortisone successfully weaned off it and restored their adrenals to full strength?

Thanks madman i had actually increased my omega 3 intake both dietary and supplement as a result of the perceived increase in omega 6s from the injections, but the math you laid out makes sense and indicates that it's not too much of an issue. Has there been any research on the health impact...

Not sure how much people pay attention to this, but there's a lot of talk in nutrition circles about avoiding manufactured seed oils like canola, cottonseed, soy, corn, safflower, peanut, etc., which people suspect to be major drivers of the chronic disease epidemic. Is there any concern for...

I will definitely check that supplement out. Much appreciated Nelson.

Hi Nelson - Thanks for checking. I have had an in lab PSG sleep test done which confirmed that I do not have apnea. Additionally, I have met with a mental health specialist for evaluation and was told that I'm all clear. I also meditate whenever possible and regularly attend 10 day silent...

Thanks and understood. Have my follow up appointment next week will be sure to bring this up.

Thanks System for the quick reply. I hear you on the low SHBG high E2 sensitive. What's your thoughts on my Free Estradiol being 1.1 so well within range? Wouldn't the free E2 be the one we are more concerned with given my SHBG?

Hi All - See below for protocols (previous and current) & latest labwork. As the title posts notes, even though my bloods look fine I'm still pretty tired and have a decent amount of brain fog. I'm in my early 30s and I've had a sleep study done which didn't show anything to be concerned about...

Hi All, I've been on Hcg pregnyl since starting TRT back in April. I just called my pharmacy to refill and they said there is a national shortage on Hcg pregnyl and suggested novarel. Does anyone have any experience with that product? Thanks

Given the article is fairly lengthy I've excerpted a portion. This seems to indicate that a simplistic approach of free hormones and SHBG may not be accurate. Taken together, the body of research on SHBG’s multiple functions puts the biomarker’s level fluctuations into context. That Joe has a...

With all the emphasis placed on the importance of SHBG and the free hormones I was wondering what people thought about the article below. Apologies if this has already been posted /discussed. Sex Hormone Binding Globulin: New Science Questions Old Beliefs

Ok thanks Mark and System that makes sense. Perhaps I misunderstood other posts where people were saying they had low SHBG and were hyper excreters and therefore needed more.