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"A decade of study has conclusively shown that the reproductive hormone kisspeptin is a critical regulator of the HPG axis acting in the hypothalamus to control GnRH secretion. More recently, the role of kisspeptin outside the HPG axis has received increasing attention with the emergence of...

Did anybody tune into the webinar? The doctor giving the presentation is a urologist not far from me.

Once you're optimized.... black coffee and a creapure creatine. Try to get everything else from food.

I had transient testicle pain, painful urination, pubic area / bladder pain. Had 5 office visits with a urologist, 8 weeks of antibiotics, and a CT scan that didn't show anything. Still wasn't getting better. Finally went to see a pelvic floor physical therapist. Things have much improved...

Anyone experience rather intense testicular aches? Trying to not use HCG as this causes it's own set of problems (Acne, loss of libido, erectile issues). Feel pretty good on straight test other than the pain in the nuts.

Hello Dr. McClain, Appreciate your time and knowledge you spend to answer questions on the forums. I recently had a 23&me dna test done and found I have a lower expression of MAO-A gene (oxidizes serotonin, dopamine, epinephrine, norepinephrine). I've been on TRT for a little over two years...

Just outside Cincinnati. In Northern KY.

Wanted to share an experience I had recently at a LabCorp facility for some routine bloodwork. The phlebotomist looks at the order and reads "Defy Medical" and make the comment, "Why don't they just call it "Get Cheap Steroids". There's apparently an increase in business they're seeing and not...

What's the take on tanning from some of the leaders in the anti-aging spectrum with regards to VitD benefits (if any) and risks associated with tanning? I know Dr. Mercola used to sell what he called "Vitamin D Beds".

Any new developments? I saw where Dr. Crisler had stated they were getting good reports back on MK-677.

I've used these for several years. I definitely notice when I forget to use them. NOW Probiotic 10-Strain, 25 billion https://www.amazon.com/Now-Foods-Probiotic-10-25-Billion/dp/B0041U6OOG/ref=sr_1_1_a_it?ie=UTF8&qid=1473544799&sr=8-1&keywords=now+probiotic+10+50+billion

Thanks doc. I sent an email to the office to see what's going on. I get all the other emails from defy without issue.

Wow. Dr. Crisler was the only consult I'd worked with up until now. Sounds like I'm not on the newsletter email or something as I didn't get the notification.

I can concur. Just started TRT again. 200mg Test, 500iu HCG 2/w, .5mg Arimidex 2/w. I've gained 10lbs within the first 5 weeks and have noticed what looks like edema in the lower legs from my dress socks. Just did follow-up labs and waiting for the follow-up appointment. Am interested to see...

Nelson, I currently meet those requirements and would be interested to know a little more about the pilot.