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LOW SHBG CURE

Gentlemen, there is a cure for Low SHBG FINALLY. And, It is tangible unlike the "keto diet and fasting". There is a newly approved drug that could easily more than double our SHBG and for many of us would mean a new life and TRT working. The drug is called Rezdiffra (Resmetirom) manufactured by...
- kashman112
- Thread
- Jun 13, 2024
- estradiol receptors shbg trt
- Replies: 10
- Forum: Testosterone Basics & Questions
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Any new discoveries on Low SHBG curse ?

I m just checking with the community to see if there is a new discovery with Low SHBG individuals ? Any new treatment ? Any new strategies to raise it ? It is a bad curse .
- kashman112
- Thread
- Dec 8, 2023
- shbg shbg advice shbg and estradiol receptor testsosterone trt
- Replies: 46
- Forum: Testosterone Side Effect Management
K
How does Thyroid hormone effect Estrogen and Aromatase?

I have searched for the answer endlessly and only got conflicting reports . Does Thyroid hormone ( T4,t3) reduce Estrogen or raise it ? What is their effects on the aromatase enzyme ? Thank you . All seems very confusing and I think the TRT/testosterone community could benefit from the correct...
- kashman112
- Thread
- Feb 12, 2023
- ai aromatase t3 t4 tesosterone thyroid thyroid dose
- Replies: 4
- Forum: Testosterone Side Effect Management
K
Toremifene Citrate

I m in the process of restarting after TRT , but Clomid is a non-starter for me and Nolvadex also gave me libido issues . I want to choose Toremifene Citrate as the SERM post HCG but my doctor says it may not be available in pharmacies . Does anybody know if that is true ? Is there a pharmacy...
- kashman112
- Thread
- Jan 18, 2023
- pct restart shbg torem toremifene trt
- Replies: 2
- Forum: Testosterone Basics & Questions
K
D-chiro-inositol raises testosterone significantly

This study confirms that D-chiro-inositol raises Testosterone significantly and lowers E2 and Estrone : https://pubmed.ncbi.nlm.nih.gov/34078260/ Why is this not talked about anywhere ? Is there something wrong with the study ? Am I missing something ?
- kashman112
- Thread
- Jan 16, 2023
- ai e2 estradiol estrogen shbg testosterone trt
- Replies: 4
- Forum: Testosterone Basics & Questions
K
How to lower IGF 1 ?

Is there a proven way or supplement for lowering IGF1 ? Besides the internet BS regarding diet .
- kashman112
- Thread
- Jan 4, 2020
- igf-1 shbg
- Replies: 17
- Forum: General Peptide Use & Information
K
Scrotal cream effect on SHBG vs injectble

For the guys who have labs on both . Does your SHBG tend to differ with injectable and Scrotal cream ? My SHBG goes from mid 20s to low teens on ANY dose or frequency of Test cyp . I was wondering if Cream is different ? Please let me know I am desperate.
- kashman112
- Thread
- Dec 2, 2019
- @shbg low shbg test cream
- Replies: 28
- Forum: Testosterone and Men's Health Articles

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038