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  1. Nelson Vergel

    hCG Plus TRT Testicular & Fertility Restoration Protocol

    Hey guys, what do you think I am missing in the downloadable attached PDF? This attached document synthesizes key findings on the use of Human Chorionic Gonadotropin (hCG) in men, either as an adjunct to Testosterone Replacement Therapy (TRT) or as a standalone monotherapy. By mimicking the...
  2. Nelson Vergel

    Deep Dive: Research on Pornography Use, "Addiction," Mood, Libido, and Sexual Function in Men

    Porn Addiction- Diagnostic Landscape and Controversy The clinical status of problematic pornography use remains contested. Compulsive Sexual Behavior Disorder (CSBD) is recognized by the WHO in the ICD-11 as an impulse control disorder, but the DSM-5 does not recognize it as a standalone...
  3. Nelson Vergel

    Practical Clinical Summary on Testosterone Therapy in Women

    Practical Clinical Summary on Testosterone Therapy in Women (From ExcelMale.com) Based on the ExcelMale forum threads and related clinical literature, here's a comprehensive extraction of practical content for a clinical article: Physiological Role & Rationale Key Functions: Testosterone...
    • Nelson Vergel
    • Thread
    • testosterone products for women testosterone women trt women
    • Replies: 0
    • Forum: HRT in Women
  4. Nelson Vergel

    How Anabolic Agents Can Save Your Muscles: One Man's Journey from Death Sentence to Thriving at 66

    The story of how testosterone therapy and anabolic agents helped transform HIV treatment and what it means for men's health today. By Rafael Zara A Death Sentence That Changed Everything Nelson Vergel was just 24 years old when doctors basically told him he was going to die. It was 1985, and...
  5. Nelson Vergel

    Options for Delayed or Absent Orgasms Despite Stimulation in Men

    Briefing: Male Delayed Orgasm and Anorgasmia Executive Summary This document synthesizes current knowledge on male Delayed Orgasm (DO) and Anorgasmia (AO), complex and often underreported sexual dysfunctions with a significant impact on quality of life. DO is defined as an increased latency to...
  6. Nelson Vergel

    The Relationship Between Testosterone Therapy and Atrial Fibrillation: A U-Shaped Curve Hypothesis

    The Relationship Between Testosterone Therapy and Atrial Fibrillation: A U-Shaped Curve Hypothesis Executive Summary An analysis of clinical research on testosterone therapy and cardiovascular health reveals a complex, non-linear relationship, particularly concerning the risk of atrial...
  7. Nelson Vergel

    NSAID Increases Muscle but Not Strength

    PODCAST Episode:
  8. Nelson Vergel

    PCT After Anabolics: Clomid versus hCG + Clomid

    Objectives To evaluate the clinical necessity and optimal pharmacological strategy for post-cycle therapy (PCT) in recreational anabolic-androgenic steroid (AAS) users with normal pre-cycle reproductive profiles. Subjects and Methods This retrospective, dual-centre cohort study included 79...
  9. Nelson Vergel

    New Testosterone Tools Web Site

    Testosterone Tools is your personal command center for mastering testosterone replacement therapy through the power of individualized data. Born from the frustration of one-size-fits-all protocols and outdated medical dogma, this platform empowers you to track, analyze, and optimize your TRT...
  10. Nelson Vergel

    Nelson Vergel, Founder of ExcelMale.com

    Nelson Vergel: A Life Dedicated to Health Advocacy and Education Early Life and Education Nelson Vergel was born on February 12, 1959, in Maracaibo, Venezuela. He studied chemical engineering at McGill University in Montreal, Canada, on a full scholarship, graduating in 1981. In 1987, Vergel...
  11. Nelson Vergel

    Tripcheck Psychedelic Support

    They will check on you during a psychedelic experience : Fireside Project Launches TripCheck: First-of-Its-Kind Scheduled Check-In Service for Psychedelic Journeys
  12. Nelson Vergel

    Natural Thyroid Medicine Under Threat by the FDA: DTE And Your Options

    The FDA just made a decision that could strip away affordable thyroid treatment for thousands of Americans - without public input, without proper science, and based on a petition from a drug company that wants a monopoly. This affects YOU if: ✓ You take natural desiccated thyroid extract...
  13. Nelson Vergel

    Peptide Dosage Calculator

    Well designed calculator : Peptide Calculator | Free & Accurate Tool for Dosage & Reconstitution
  14. Nelson Vergel

    List of Over 65 Peptides, Their Use, and Common Dosages

    List of peptides and other molecules, their uses, and commonly used dosages. Ready to dive deep into peptide therapy? This massive guide covers 65+ peptides with exact dosages, clinical references, and uses—from BPC-157 to Semaglutide to Epithalon. The most comprehensive resource I've seen...
  15. Nelson Vergel

    Men Given Testosterone Enforce Fairness More Readily.

    The study examined how giving men extra testosterone affects their behavior. It found that when men were given testosterone from an outside source, they were more likely to punish others who behaved unfairly—even when it cost them something. For example, if someone acted unfairly, men on...
  16. Nelson Vergel

    How to Prevent and Reverse Erectile Dysfunction

    How to Prevent and Reverse Erectile Dysfunction: Your Complete Guide to Getting Hard and Staying Strong Bottom Line Up Front: You don't have to accept erectile dysfunction as your new reality. Whether you're dealing with occasional difficulties getting hard or consistent challenges maintaining...
  17. Nelson Vergel

    Factors Involved in Sex Drive and Erection Quality: Beyond Testosterone

    The Complex Neurochemistry of Male Sexual Function: Understanding the Biological Foundations of Desire and Performance Male sexual function represents one of the most intricate orchestrations of neurochemical, hormonal, and physiological processes in human biology. Far from being a simple...
  18. Nelson Vergel

    How Your Circadian Clock Genes Affect Your Testosterone- Deep Dive

    This Beyond Testosterone podcast episode comes from an academic review article from the Asian Journal of Andrology, published in September-October 2025. This article, titled "Regulation of testosterone synthesis by circadian clock genes and its research progress in male diseases," examines the...
  19. Nelson Vergel

    Ibogaine: Promise and Practicalities for Transforming Addiction Treatment

    Ibogaine: Promise and Practicalities for Transforming Addiction Treatment Ibogaine is rapidly garnering attention as a potentially revolutionary treatment for addiction and related mental health disorders—a beacon of hope in landscapes often characterized by despair and systemic inadequacy...
    • Nelson Vergel
    • Thread
    • drug addiction ibogaine psychedelics; depression; anxiety; ptsd; addiction
    • Replies: 2
    • Forum: Mental Health
  20. Nelson Vergel

    The FDA is seeking your comments on black box warning for women's hormone therapy

    The FDA is seeking comments on black box warning for women's hormone therapy The FDA is currently seeking public comments regarding the black box warning on women’s hormone therapy products for menopause. Here’s what you need to know: Background: Since the early 2000s, all estrogen-containing...
  21. Nelson Vergel

    Caffeine and its metabolites- Comparison

    Here’s a comparison of Caffeine, Paraxanthine, and Theophylline, focusing on their structure, effects, metabolism, and common uses: Comparison Table: Caffeine vs Paraxanthine vs Theophylline Feature Caffeine Paraxanthine Theophylline Chemical Name 1,3,7-trimethylxanthine...
  22. Nelson Vergel

    What is the Optimum TRT Dose for Muscle Growth? : Nelson Vergel Reviews the Data

    Landmark Study Reveals How Different Testosterone Doses Affect Muscle, Fat, and Health Markers in Young Men A deep dive into one of the most influential studies on testosterone dosing reveals key takeaways for anyone interested in hormone optimization—a topic of persistent debate in men's...
  23. Nelson Vergel

    The Link Between Muscle Quality and Erectile Dysfunction

    Briefing Document: The Link Between Muscle Quality and Erectile Dysfunction Date: July 21, 2025 Source: "Exploring the link between muscle quality and erectile dysfunction: assessing the impact of mass and strength" (Sexual Medicine Reviews, 2025) I. Executive Summary This briefing document...
  24. Nelson Vergel

    Subscribe to our podcast on Spotify

    Please subscribe by clicking on this link: Beyond Testosterone Podcast- Curated by Nelson Vergel - Excel Male TRT Forum
  25. Nelson Vergel

    Beyond Testosterone Podcast- Curated by Nelson Vergel

    Unlock the latest science, expert interviews, and practical strategies for optimizing men's health by subscribing to the Nelson Vergel Beyond Testosterone Podcast. Whether you're seeking real-world advice on testosterone therapy, maximizing muscle growth, improving fat loss, or understanding...
  26. Nelson Vergel

    Optimizing Fat Loss and Muscle Preservation: Tirzepatide + Oxandrolone + TRT + Protein & Exercise

    This article outlines a comprehensive strategy for optimizing fat loss and muscle preservation, primarily discussed within the context of an online forum dedicated to men's health, ExcelMale.com. The core of the strategy involves a multi-faceted approach combining specific pharmacotherapies...
    • Nelson Vergel
    • Thread
    • anavar creatine egg whites empower pharmacy fat burners fat loss glp-1 mounjaro muscle building oxandrolone tirzepatide tirzepatide dosing whey protein
    • Replies: 7
    • Forum: Weight Loss Options
  27. Nelson Vergel

    New Podcast Episode: All About Oxandrolone (Anavar)

    This podcast session examines the efficacy and safety of oxandrolone, an anabolic androgenic steroid (AAS), in treating various wasting and catabolic disorders. It explores the drug's pharmacokinetic and pharmacodynamic properties, noting its unique resistance to liver metabolism compared to...
  28. Nelson Vergel

    How U.S. Blood Banks Handle Therapeutic Phlebotomy for Men on Testosterone Replacement Therapy (TRT)

    How U.S. Blood Banks Handle Therapeutic Phlebotomy for Men on Testosterone Replacement Therapy (TRT) Blood centers have had to adapt their policies because the polycythemia/erythrocytosis that often accompanies TRT creates both medical need (frequent blood removal) and regulatory challenges (how...
  29. Nelson Vergel

    Can Certain Blood Pressure Medications Decrease Hematocrit?

    ARBs, or Angiotensin II Receptor Blockers, are a class of medications primarily used to treat high blood pressure (hypertension). They also play a role in managing heart failure and protecting kidney function, particularly in patients with diabetes. ARBs work by blocking the effects of...
  30. Nelson Vergel

    How Compounding Pharmacies Are Challenging Big Pharma on Fair Access

    13-Minute Podcast: This podcast discussion examines the burgeoning role of compounding pharmacies, particularly in the context of GLP-1 medications, and how they are challenging the established dominance of Big Pharma. Driven by soaring drug costs, supply shortages, and a demand for...
  31. Nelson Vergel

    TRT vs Clomiphene: Effect on IGF-1

    Key human studies that have measured circulating IGF-1 after giving testosterone, clomiphene or enclomiphene # Intervention (dose & route) Study population & design Treatment length Mean change in IGF-1* Notes 1 Testosterone enanthate 300 mg IM weekly 11 healthy young men, double-blind...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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