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    Where to buy peptides?

    Assuming you're in the United States: Many of these peptides are not FDA approved and cannot legally be sold for human use. With respect to the ones that are approved, they generally require a prescription and must be made at approved facilities. All of this regulation is bypassed when the...
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    High Testosterone, is this expected?

    This is not too unusual. There's at least one study finding absorption via scrotal skin to be over 50%. Consider that healthy young men typically produce 6-7 mg of testosterone daily. You're potentially getting into the realm of four times that with your two doses. It's different at other...
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    Starting TRT Soon

    Not above average, above range. This means more than two standard deviations above average. In general there are all kinds of negative associations when hormones are out of range, not least of which is reduced longevity. Although long-term research is lacking, specific to testosterone there are...
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    Starting TRT Soon

    It's the opposite. The majority should not be dosed excessively just because the more-is-better minority is louder and more demanding. No, it isn't. It makes no sense to start TRT at a dose that is effectively above the physiological production range. Even the recommended starting dose for...
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    enclomiphone lowered my testosterone

    Throwing out a couple possibilities: Your SHBG dropped between the measurements, such that an increase in free testosterone was concealed. Or you actually have primary hypogonadism, i.e. testicular insufficiency. Have you tested LH?
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    GHK-cu and DHT

    I agree that Peptide Sciences is considered the most trustworthy, though ironically I have had a couple of QC issues with them. I also use Nootropic Source because they have a good price on GHK-Cu in quantity. However, I have not done any independent testing to quantify things.
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    Starting TRT Soon

    It's likely much more testosterone than you could ever have produced naturally, heightening your risk of side effects. But I'm primarily emphasizing a low-and-slow approach. If you had started low and slowly titrated up to this while seeing improvements then I would not characterize it as an...
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    GHK-cu and DHT

    We're largely on our own with this. There's this frequent argument that we should take breaks, but it seems to be based more on speculation and caution than anything concrete. Assuming copper intake is reasonable, my hope is that as with testosterone, the short half-life and pulsatile delivery...
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    Starting TRT Soon

    The main argument is that you should establish a baseline at physiological levels, so that if you as an informed adult want to experiment with higher levels then at least you'll know if you're making things better or worse. All too often people feel bad starting with high levels and then assume...
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    Starting TRT Soon

    Don't ignore the key qualification in my posts: starting out Even so, I can point to Xyosted. Only three doses, 50, 75 and 100 mg TE per week, which are obviously covering the vast majority of men. For reader clarity: note the difference between pure testosterone and testosterone cypionate...
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    Starting TRT Soon

    Let's see the documentation. What is the incidence of this purported condition? One in tens of thousands? I'm betting it has essentially no bearing on the average guy starting TRT. So what. Are you aware that the normal production range is about 3-9 mg per day? Yet you're defending starting out...
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    Starting TRT Soon

    That's 12 mg a day of testosterone, more than almost every man makes naturally. Of course it's too much. I don't see how anybody can defend starting out with a dose this high or higher. This should only happen if you tell your doctor that anabolism is your number one priority and you knowingly...
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    Why do most say other hormones deplete while on TRT?

    While it's unequivocal that exogenous testosterone can affect a large number of other hormones/precursors by disrupting various feedback loops, the argument would be that it's statistical in nature, with substantial variation between individuals. It's more clear-cut with hormones such as LH and...
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    Syringe Holder/Loader

    Another simple option, a piece of stiff wire bent to hold the vial and hang it from something. A wood chip, syringe cap, etc. holds the plunger out:
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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