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Defy Medical TRT clinic doctor
  1. Vince

    Are you losing your Y chromosomes?

    https://www.earth.com/news/y-chromosome-disappearance-study-finds-direct-link-to-much-greater-cancer-risk/#google_vignette
  2. Vince

    Overthinking

    Overthinking involves excessive rumination on thoughts and situations, often leading to distress and difficulty with decision-making. It can be a symptom of anxiety, depression, or other mental health conditions, but can also be a learned behavior or a response to stress. Strategies for managing...
  3. Vince

    Limited lab testing by endocrinologists

    A lot of times. I think we overthink it. You can keep it simple and do just as good as someone doing multiple tests. Most men do good on simple protocol.
  4. Vince

    Higher IQ Linked to Testosterone Exposure In Utero

    Personally, I don't believe it. I have kids and grandkids with over 130 IQs. Top 2% in comprehension and math. Their T is not super high.
  5. Vince

    Clomid for Testicular Shrinkage ?

    Yes
  6. Vince

    Clomid for Testicular Shrinkage ?

    Does it cause any issues?
  7. Vince

    Clomid for Testicular Shrinkage ?

    Personally, I've never had any issues with estrogen. My e2 runs on a low end of range. It doesn't mean others don't have issues with estrogen.
  8. Vince

    PTSD and Dementia Risk: A Potential Target for Early Intervention

    Alzheimer’s Risk Linked to Increased Social Activity. Contrary to popular belief, a new study suggests that people with a higher genetic risk for Alzheimer’s may become more socially engaged—not less. Researchers analyzed data from over 500,000 individuals and found that higher-risk participants...
  9. Vince

    Male...gaining slight fat with cellulite in thighs all of a sudden even with normal lab results

    As most members of this forum knows Belly fat is unhealthy fat. Below the waist is healthy fat. I would concentrate on squats and lots of walking it should firm up any fat you have on your hips or legs. I also had nerve damage in my right leg and tendon damage in my left leg. From when I broke...
  10. Vince

    Best testosterone injection site, no aspiration needed, avoids all nerves

    You could just inject in your shoulder.
  11. Vince

    Best testosterone injection site, no aspiration needed, avoids all nerves

    If you slightly pick up your leg you will feel the muscle get hard right below your hip bone and slightly to the back. That's where you inject.
  12. Vince

    Morning erection won’t go down without help

    It's normal even for a 70-year-old man like me
  13. Vince

    Sperm result after 3 months of HCG. What would you do?

    Stop TRT for now. If I was in your shoes I would definitely first try clomid. I believe it will be the best bet for you to become fertile again. It appears that most do better with low dose clomid, 12.5mg everyday or every other day or sometimes twice a week. You can buy it in Mexico or...
  14. Vince

    VO2 Max: The Gold Standard

    AI Overview While both VO2 max and strength are strong indicators of longevity, VO2 max is considered the most robust predictor. However, strength, alongside muscle mass, plays a significant role in overall health and lifespan. VO2 Max: The Gold Standard Definition: VO2 max, or maximal...
  15. Vince

    Dosages

    Exactly we are all different and need different levels. You should read Florence's book I think you would find it very interesting and educational.
  16. Vince

    Dosages

    Calm down
  17. Vince

    Dosages

    https://www.excelmale.com/threads/why-do-some-men-need-supraphysiological-doses-of-testosterone-to-achieve-normal-levels.32512/post-298802
  18. Vince

    Dosages

    I say would say a good starting dose would be 50 mg of T and 500 IU of HCG combined in the same syringe. My understanding is that's @Nelson Vergel protocol. Here's mine. I just had Labs done yesterday will post when available...
  19. Vince

    Dosages

    No. What I mostly see is younger men need lower doses. The reason behind it is when you were at your peak. What was your T level at. Most younger men had lower levels when they were at their peak. Older men had higher levels when they were at their peak, so now the older men need higher levels...
  20. Vince

    Testosterone dropped after a few months on the same dose

    Your first labs were done after 8 weeks. Not long enough. You need to wait at least 12 weeks. So your 2nd Labs I would consider more accurate. Every time you do Labs they will vary. Injecting is not 100% accurate and of course vial strength will vary. I feel my best at higher levels so I see...
  21. Vince

    Reassessing the evidence of a survival advantage in Type 2 diabetes treated with metformin

    https://www.sciencealert.com/common-diabetes-drug-linked-to-exceptional-longevity-in-women
  22. Vince

    Clomid for Testicular Shrinkage ?

    I now inject 500 IU of HCG every third day. I combine T and HCG in the same syringe, like Nelson. It's not true about desensitization.
  23. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    That's exactly what Florence Comite talks about in her book and practice. https://en.m.wikipedia.org/wiki/Florence_Comite
  24. Vince

    Does arthritic elbow mean I can't lift weights?

    This is what worked for me. Of course it may not work for you. I had tennis elbow about 3 years ago, it was very painful. I had to resort to pull-ups and chin-ups really stretch out my elbow. It did work for me. Now I'm completely pain-free.
  25. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    AI Overview Based on the provided search results, the UGT2B17 gene plays a significant role in testosterone metabolism and clearance, specifically through glucuronidation, a process that makes testosterone easier to excrete. Individuals with a deletion in the UGT2B17 gene show reduced...
  26. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    CYP17A1: This gene plays a role in the synthesis of testosterone.
  27. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    https://www.excelmale.com/forum/showthread.php?1403-Are-you-a-fast-metabolizer-of-medicines&highlight=Fast+metabolizer
  28. Vince

    Cannabis and DHT

    When I looked it up not everyone can gets a positive reaction from cannabis
  29. Vince

    Cannabis and DHT

    Does cannabis increase your libido and orgasms?
  30. Vince

    3 hours of sleep and no fatigue?

    For decades, the mantra has been the same: adults should aim for seven to eight hours of uninterrupted sleep each night for optimal health, performance, and longevity. From doctors to wellness influencers, the message has echoed across platforms, backed by countless studies linking insufficient...
  31. Vince

    Big subjective difference between compounded hCG and Pregnyl

    Personally I never noticed a difference between the two.
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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