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Defy Medical TRT clinic doctor
  1. BadassBlues

    Metabolic Fitness and Mitochondrial Health

  2. BadassBlues

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

    Macroautophagy involves the formation of double-membrane vesicles called autophagosomes that engulf larger cellular components, while microautophagy directly engulfs cytoplasmic material into lysosomes through membrane invagination. Both processes are essential for cellular recycling and...
  3. BadassBlues

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

  4. BadassBlues

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

    https://pmc.ncbi.nlm.nih.gov/articles/PMC3740586/ Autophagy and mitophagy in cellular damage control Jianhua Zhang 1,⁎ Author information Article notes Copyright and License information PMCID: PMC3740586 NIHMSID: NIHMS494864 PMID: 23946931 Autophagy and mitophagy are important cellular...
  5. BadassBlues

    Sexual Devices for Vulva Owners

    I just bought my wife this for her birthday. Too early for any feedback, but it's fun watching her use it ;) https://yarlap.com/products/the-yarlap-kegel-exercise-kit-system
  6. BadassBlues

    Sexual Devices for Vulva Owners

    The short answer is no. Vulva's do not depreciate the way Volvos do. If you were to go to a dealership and try to trade in your Vulva, you would likely end up in jail. Vulvas get far better mileage than Volvos, thus they have a much longer lifespan. And while I do enjoy driving, the pleasure I...
  7. BadassBlues

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

    Can we move this thread to the Health Span Extension forum? I have a feeling this one is going to catch fire.
  8. BadassBlues

    The New Standard in NAD-Boosting

    They also have a self injection product: https://wellsrx.com/product/niagen-plus/
  9. BadassBlues

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

    I believe that some European countries have strict supplement guidelines. I agree that we should have that as well. Just as long as it doesn't become corrupt like the FDA. I also agree that the basics should be paramount to any supplement or drug. But I can see real potential in this one for...
  10. BadassBlues

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

    Good information. Obtaining the patent and FDA approval was an expensive endeavor. That allows for statements to be made as to efficacy, which is a major part of their marketing. Also, being in sales for most of my life, a higher priced product has a certain appeal in that it makes it appear to...
  11. BadassBlues

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

    Taking into consideration the half-life of Urolithin A, which is 17 to 22 hours, dosing would appear to be best taken daily. Recommended dosages range from 250 mg to 1000 mg. Most of the studies indicate that the ideal dose is age dependent. As a younger person, a dose of 250 mg might be...
  12. BadassBlues

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

    https://pmc.ncbi.nlm.nih.gov/articles/PMC9229509/ Ameliorative Effects of Gut Microbial Metabolite Urolithin A on Pancreatic Diseases Kailin Li 1, Yao Xiao 1, Ji Bian 2, Lin Han 1, Caian He 1, Emad El-Omar 3, Lan Gong 3,*, Min Wang 1,* Editor: LaVerne L Brown Author information Article...
  13. BadassBlues

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

    https://www.sciencedirect.com/science/article/pii/S1568163724002241 Targeting aging with urolithin A in humans: A systematic review Author links open overlay panelAjla Hodzic Kuerec a b, Xuan K. Lim a b, Anderson LY. Khoo a b, Elena Sandalova a b, Lihuan Guan a b, Lei Feng a b c, Andrea B...
  14. BadassBlues

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

    After some research on available products and questions regarding dosage, it appears there is a wide margin between different manufacturers. Time Line who offers the Mitopure ingredient is expensive at over $100.00 per month with a recommended dosage of 500 mg...
  15. BadassBlues

    Vitamin D May Slow Cellular Aging

    I take 2000 IU’s plus K2. I also take a blend of calcium, magnesium and potassium.
  16. BadassBlues

    Anyone got a solid recipe for making scrotal testosterone cream (using testosterone base)?

    Use unestered T if possible. I use both DMSO cream and Phlojel Ultra as a base. The last few jars of DMSO burned like Hell, so I am not currently recommending that until they get it figured out. So, start with the Phlojel base: https://www.jarpharmaceutical.com/phlojel-ultra You will need a...
  17. BadassBlues

    List of Over 65 Peptides, Their Use, and Common Dosages

    The main reason is that they actually took Tesamorelin, a new peptide to the finish line with an FDA approval. Since Ipamorelin was already in use and readily available, there was no money in it. Ipam will give you the same results sans the FDA approved label. For a lot less money ;)
  18. BadassBlues

    List of Over 65 Peptides, Their Use, and Common Dosages

    Tesamorelin vs. Ipamorelin: Properties Tesamorelin is approved for the treatment of HIV-associated lipodystrophy. This very narrow approval belies the peptide's wider use as an agent for altering body composition. Research indicates that Tesamorelin can reduce fat mass, boost muscle and bone...
  19. BadassBlues

    Sex Hormone-Binding Globulin (SHBG): Biology and Biomarker

    SHBG without question is one of the most least understood aspects of hormonal function. Great post!
  20. BadassBlues

    Crypto for buying pepetides

    I use Moon Pay.
  21. BadassBlues

    Crypto for buying pepetides

    Most all peptide suppliers take credit cards. Crypto is mainly used by those selling less than legal items, sometimes it's a necessary evil, but not for peps. If you have a peptide site asking for crypto, you should move on as that is a red flag. They are likely based in China, which isn't...
  22. BadassBlues

    UCLA’s Hair Growth Breakthrough: The Science Behind PP405 & the Future of Baldness Treatment

    https://www.excelmale.com/threads/pp405-possible-breakthrough-treatment-for-hair-loss.32059/
  23. BadassBlues

    Where to Find Info on Peptide Dosing and Reconstituting

    You should post this as a sticky.
  24. BadassBlues

    Help with peptides!!

    Thats a good combo. You can buy it premixed together or separately. I prefer separately myself as I can adjust the dosage of each as I need to. Peptide Sciences is the best choice. They are reliable and you know what you are getting. There is a lot of junk that comes out of China which is why...
  25. BadassBlues

    Testosterone dosing amounts in postmenopausal women?

    I would, but I dumped FB and all other social media platforms a few years back. Look like you have quite a good following though.
  26. BadassBlues

    Testosterone dosing amounts in postmenopausal women?

    I would like to see some anecdotal reviews of the benefits (and side effects) from women on testosterone. It would be nice to hear it directly from the women themselves.
  27. BadassBlues

    Peptides supplier??

    I have never heard of them, but there are dozens of suppliers anymore. Peptide Sciences is the most reliable. They are not always the cheapest, but the quality is unmatched.
  28. BadassBlues

    Is Omega 3 an AR killer??

    Most of the research on this topic is prostate cancer related.
  29. BadassBlues

    Is Omega 3 an AR killer??

    Interesting question, where did you get the idea to ask it? Here is an interesting rat study, a bit off your question but still relative: https://pmc.ncbi.nlm.nih.gov/articles/PMC8260291/ 5. Conclusions The present study revealed for the first time the potential effects of omega-3 and omega-6...
  30. BadassBlues

    Interesting injury

    I am a lifelong gym rat and have managed to keep myself in good shape, but I can feel the difference as I get older. We just wear down over time and some parts just can't handle the same stress as they did when we were younger. Like you, I still give myself energetic workouts, but I don't do...
  31. BadassBlues

    Interesting injury

    I'm 68, if you are going to work out your neck at our age, start very slow with no weights at all for a while to adjust to the motion and get the correct form. Then do light weight only. The cervical discs in an aged spine are not something you want to push too hard.
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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