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  1. K

    Irregular libido and night sweats

    I do not have labs to post. My endo shares the info, but does not provide a copy of the results. I am working with a different paradigm than most people on this site. I see my endo primarily for type 2 diabetes; therefore, the bulk of my lab data points are for diabetes, not low-T. TRT came...
  2. K

    Irregular libido and night sweats

    I am not going to do daily injections. That defeats the purpose of using IM testosterone. What I need to know are the data points that are not part of my blood tests. Right now, I am just shooting in the dark. I do not feel horrible or experience night sweats every day, nor do I experience...
  3. K

    Irregular libido and night sweats

    I decided that it is time to post an update. I attempted to go off of TRT, but could not do it. I had a particularly bad weekend this past weekend. After a several good and a couple of very good weekends where my libido was off of the charts, it was non-existent this weekend. I woke up in a...
  4. K

    Irregular libido and night sweats

    The night sweats are definitely not glucose. I have a glucometer on my nightstand that I use to test for lows and highs at nights. I have very well-controlled diabetes. The night sweats are definitely due to TRT. I do not have night sweats when I am not on TRT. I am talking about having to...
  5. K

    Irregular libido and night sweats

    Well, it is definitely TRT that is causing the night sweats. I am on generic Axiron, which is fairly conservative compared the TRT protocols used on this forum. I skipped a day and no night sweats. I am going to discontinue use because the benefits I felt at first have vanished, and now the...
  6. K

    Irregular libido and night sweats

    I think that the only way that is going to work is if the doctor who handles testosterone problem is a urologist as part of sexual function medicine; otherwise, I am looking at switching endocrinologists. The problem is that testosterone production is part of the endocrine system. I actually...
  7. K

    Irregular libido and night sweats

    Lately, there are times when my libido is supercharged and times when I could not raise an erection if I downed an entire bottle of PDE5is. I am also suffering from night sweats that occur between 2 and 4am, which tells me that it is probably hormonal. Nothing has changed except for the fact...
  8. K

    Teva's generic taladafil is now being dispensed in U.S. pharmacies.

    Teva's offering is definitely new. Tadalafil Generic for ED Announced for US Market
  9. K

    Teva's generic taladafil is now being dispensed in U.S. pharmacies.

    My pharmacy only lists my co-pay and the cash price on the receipt. The PBM that manages my plan negotiates their price. I am certain that it is not the cash price.
  10. K

    Teva's generic taladafil is now being dispensed in U.S. pharmacies.

    Full retail is over $500.00 for 8 tablets. However, that is not what Rx insurance is paying.
  11. K

    Teva's generic taladafil is now being dispensed in U.S. pharmacies.

    Puerto Rico is a U.S. territority and Eli Lilly owns the plant. Lilly Puerto Rico 235 Federico Costa Street Parque Las Américas I, Suite 401 San Juan, Puerto Rico 00918 +1-787-753-7070 My ex works in the pharmaceutical industry. She she used to work in regulatory. A drug that is sold in the...
  12. K

    Teva's generic taladafil is now being dispensed in U.S. pharmacies.

    I do not know if it is news, but I refilled my Cialis prescription the other day and was surprised when my co-pay was $10.00 instead the normal $25.00 that I am charged for pharmaceuticals that are still on patent. I have not had that script filled for a couple of months because it is more of...
  13. K

    Low-intensity shockwave therapy for erectile dysfunction in kidney transplant recipients.

    I underwent the procedure last fall. It took a lot longer to see results than the company who is pushing the procedure in the United States claims, but it worked for me. I was hit or miss with a PDE5i before the procedure. By March, I was starting to achieve firm erections and morning wood...
  14. K

    Viagra or Placebo: Surprising Results From a New Study

    There is definitely a stress component to ED. Stress increases epinephrine production, which prevents the blood vessels in the penis from dilating.
  15. K

    Low SHBG - Lower Total T and Feeling Great

    I was referring to free T in this sentence.
  16. K

    End of patent protection for Viagra and Cialis in the United States

    With patent protection for Viagra and Cialis coming to a close a United States (U.S.) and Lilly's push to take Cialis over the counter, I am curious as to how the post-patent pricing model will look. Granted, both companies have fought like the ****ens to extend patent protection with some...
  17. K

    E2 levels for low SHBG guys

    The visceral fat -> aromatase ->E2 -> more visceral feedback loop is vicious. As far as I am concerned, visceral fat is evil.
  18. K

    Alcohol used in the production of testosterone esters?

    That is interesting. The hydroxyl group from testosterone is lost along with a hydrogen atom from the hydroxyl group in propionic acid, forming the H2O molecule residue during the condensation reaction that results in testosterone propionate. So esterase is responsible for catalyzing the...
  19. K

    Alcohol used in the production of testosterone esters?

    The body just reverses the condensation reaction via hydrolysis by inserting an H2O molecule to free the testosterone molecule from the cypionic acid molecule. C27H40O3 + H2O -> C19H28O2 + C8H14O2 My next question is what enzyme serves as the hydrolysis reaction catalyst?
  20. K

    Alcohol used in the production of testosterone esters?

    So the condensation reaction for testosterone cypionate is between testosterone and cypionic acid? C19H28O2 + C8H14O2 -> C27H40O3 + H2O The five carbon ring with the hydroxyl (OH) group is easy to see in the image below on the right. My knowledge of organic chemistry was obtained from...
  21. K

    Need some Life/marriage advice and why I've been MIA

    I am divorced as well, and I concur with Vince's assessment of the situation. The last ten years of my marriage were intimate contact free. I too thought that I was doing the right thing for my children, but the damage that staying does to one as a man as well as one's children is not worth...
  22. K

    E2 levels for low SHBG guys

    Thanks for creating this thread, Vince. I am also a low SHBG guy. That is how I was able to survive and build muscle in the gym on a total T of 240 ng/dl before I went back on TRT. I read a publication where the investigator stated that free T is a better indicator of low T than total T.
  23. K

    Alcohol used in the production of testosterone esters?

    I am assuming that testosterone esters are testosterone bound to an ester. From organic chemistry, we know that an ester is an alcohol bound to a carboxylic acid, which is an organic acid that contains a carboxyl group (i.e., an acid with a chemical formula that ends in COOH). In the case of...
  24. K

    Cialis, hit or miss

    Yes, the inconsistent response to PDE5 inhibitors is my concern. I am happy with a total testosterone of around 400 and free testosterone in the mid-12 range. The only problem I currently have with respect to TRT is a bit of bloating, mostly in my face and neck. I suspect that I am going to...
  25. K

    Cialis, hit or miss

    I underwent coronary artery bypass graft surgery in 2016 due to hereditary low HDL. None of my doctors will prescribe daily Cialis because it prevents the use of nitroglycerin in the case of an emergency. I had to get cleared by my cardiologist before my endocrinologist would put me back on...
  26. K

    Cialis, hit or miss

    I have had instances where Cialis worked better the following morning than it did the previous evening. However, there are occasions where it does not work at all. We are talking about no response whatsoever. I am using Eli Lilly's product, so it should not be a tablet-to-tablet quality issue.
  27. K

    Cialis, hit or miss

    Cialis is a total bust on the days that it does not work. I have experienced the same problem with Viagra as well. I am a type 2 diabetic, so that comorbidity complicates the picture. My endocrinologist currently prescribes my ED medication, but I am thinking about seeing a urologist to see...
  28. K

    Cialis, hit or miss

    Has anyone else experienced problems with Cialis being hit or miss? I love Cialis when it works, but there are days where it feels like I ingested a sugar pill. I always take Cialis (20mg) on an empty stomach.
  29. K

    Blood Glucose and A1C show improvement, blood meter showing rise in blood sugar lately?

    I am to the point where I never recommend a low-carb diet to diabetics because the diet is far too restrictive for the average person to maintain. The human body was not designed to live as a pure carnivore. Diabetes is an inflammatory disease. Meat, dairy, and eggs are all sources of...
  30. K

    Blood Glucose and A1C show improvement, blood meter showing rise in blood sugar lately?

    I am not 100% sold on low-carb diets for all pre-diabetics and type 2 diabetics. I was a diagnosed pre-diabetic for eight years before being diagnosed as a full-blown diabetic. Everything I was told about managing blood sugar did not work for me. All I did was get sicker. I finally...
  31. K

    Low SHBG - Lower Total T and Feeling Great

    That was a LabCorp blood test. I do not recall the top-end value, but I do believe that my value was mid-range. Low SHBG is common with type 2 diabetes. My hbA1C was 5.8, which is very good for a type 2 diabetic. I always get better numbers when I am on TRT. I also work out a lot harder when I...
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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