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  1. P

    Kisspeptin suppression under TRT: Can it affect mood and libido?

    "A decade of study has conclusively shown that the reproductive hormone kisspeptin is a critical regulator of the HPG axis acting in the hypothalamus to control GnRH secretion. More recently, the role of kisspeptin outside the HPG axis has received increasing attention with the emergence of...
  2. P

    Jatenzo, an Oral Testosterone Replacement Therapy

    Did anybody tune into the webinar? The doctor giving the presentation is a urologist not far from me.
  3. P

    Supplements used for lifting

    Once you're optimized.... black coffee and a creapure creatine. Try to get everything else from food.
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    Causes of lower back and testicle pain

    I had transient testicle pain, painful urination, pubic area / bladder pain. Had 5 office visits with a urologist, 8 weeks of antibiotics, and a CT scan that didn't show anything. Still wasn't getting better. Finally went to see a pelvic floor physical therapist. Things have much improved...
  5. P

    Testicular Ache but Do Not Want to Use HCG

    Anyone experience rather intense testicular aches? Trying to not use HCG as this causes it's own set of problems (Acne, loss of libido, erectile issues). Feel pretty good on straight test other than the pain in the nuts.
  6. P

    Ask Dr Rand McClain

    Hello Dr. McClain, Appreciate your time and knowledge you spend to answer questions on the forums. I recently had a 23&me dna test done and found I have a lower expression of MAO-A gene (oxidizes serotonin, dopamine, epinephrine, norepinephrine). I've been on TRT for a little over two years...
  7. P

    LabCorp Attitude

    Just outside Cincinnati. In Northern KY.
  8. P

    LabCorp Attitude

    Wanted to share an experience I had recently at a LabCorp facility for some routine bloodwork. The phlebotomist looks at the order and reads "Defy Medical" and make the comment, "Why don't they just call it "Get Cheap Steroids". There's apparently an increase in business they're seeing and not...
  9. P

    Tanning - VitD - Anti-Aging

    What's the take on tanning from some of the leaders in the anti-aging spectrum with regards to VitD benefits (if any) and risks associated with tanning? I know Dr. Mercola used to sell what he called "Vitamin D Beds".
  10. P

    Oral GH Booster MK-677 (ibutamoren) Side Effects and Benefits

    Any new developments? I saw where Dr. Crisler had stated they were getting good reports back on MK-677.
  11. P

    Probiotics - Recommendations for a good brand

    I've used these for several years. I definitely notice when I forget to use them. NOW Probiotic 10-Strain, 25 billion https://www.amazon.com/Now-Foods-Probiotic-10-25-Billion/dp/B0041U6OOG/ref=sr_1_1_a_it?ie=UTF8&qid=1473544799&sr=8-1&keywords=now+probiotic+10+50+billion
  12. P

    Dr Crisler out at Defy?

    Thanks doc. I sent an email to the office to see what's going on. I get all the other emails from defy without issue.
  13. P

    Dr Crisler out at Defy?

    Wow. Dr. Crisler was the only consult I'd worked with up until now. Sounds like I'm not on the newsletter email or something as I didn't get the notification.
  14. P

    HCG and Water rentention

    I can concur. Just started TRT again. 200mg Test, 500iu HCG 2/w, .5mg Arimidex 2/w. I've gained 10lbs within the first 5 weeks and have noticed what looks like edema in the lower legs from my dress socks. Just did follow-up labs and waiting for the follow-up appointment. Am interested to see...
  15. P

    Apigenin can make you a STAR! By Jerry Brainum

    Nelson, I currently meet those requirements and would be interested to know a little more about the pilot.
Buy Lab Tests Online
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic

Beyond Testosterone Podcast

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