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  1. M

    PEPTIDE RESULTS IN: IGF-1, testosterone, etc.

    So, 100mcg in a.m. and 100mcg in p.m. as an example. Any thoughts as to the risks of elevated IGF-1 levels from the GH secretagogues?
  2. M

    CCTA vs CAC scan to detect atherogenic plaque

    Has anyone done a CAC scan and CCTA and observed a wide difference in results? My recent CCTA (coronary computed tomography angiography; see below) showed "no evidence of coronary atherosclerotic plaques or coronary artery stenosis". This is in direct contrast to the CAC scan I had done in 2021...
  3. M

    PEPTIDE RESULTS IN: IGF-1, testosterone, etc.

    Big n-1 results update. With all the gym bros telling me for the last 10 years that GH secretatgogue peptides are a scam and a waste of $$$$ - and that good ol' GH is superior and the only way to go - - - Let me preface this post by saying that these peptides do work. I repeat. THESE PEPTIDES...
  4. M

    Latest Update on Metformin

    A recent metformin study casts doubts on longevity indications Thoughts?
  5. M

    Bubble gut – VAT, SAT, both - or something else

    Is this an alien baby about to burst out of me? You can see the protruding midline bulge when I lay on my back and tilt my neck up. You can also see an umbilical hernia. I really wonder whether specific PT core exercises will fix this over time - or if this will eventually require surgery. I...
  6. M

    Carpal tunnel symptoms and peptides

    I'm already taking Telmisartan and it still ddn't subside. Strange.
  7. M

    Carpal tunnel symptoms and peptides

    Anybody experience carpal tunnel syndrome symptoms (i.e. numbness in index finger, thumb and middle fingers) and body aches from GH peptides (tesamorelin, ipamorelin, etc.) especially when waking? I understand that CTS is a very common side effect with GH itself. What did you do to remedy it? I...
  8. M

    BPC-157 / TB-500 Dosage for Men

    I have done independent purity analysis of Peptide Sciences peptides including BPC-157 and all have come out at least 99% pure. I was formally skeptical about using any non-pharma-grade research peptides. Although I have not used nor tested other purveyors, Limitless Nootropics is one of the...
  9. M

    Lean mass loss on GLP-1 receptor agonists: a downside of the “miracle drugs”

    Which one did you try? From your DEXA scan, it sounds like it did its job.
  10. M

    Lean mass loss on GLP-1 receptor agonists: a downside of the “miracle drugs”

    Has anyone done a DEXA scan before and during use of any GLP-1 agonists (semaglutide, tizepatide) to assess body composition? In Peter Attia's recent blog, he eludes to the fact the GLP-1 agonists can cause loss of lean mass (in addition to fat loss), of particular concern in non-obese persons...
  11. M

    Bubble gut – VAT, SAT, both - or something else

    Thanks. SIBO has been a likely issue. Already on Metformin (as a geroprotective and prediabetes prevention) and have been taking betaine HCL and pancreatin for years. I have done extensice gut biome testing. I tend toward IR, hence the metformin and many other supplements + LC diet. Working on...
  12. M

    Steroid Belly: Anabolic Steroids Increase Visceral and Decrease Subcutaneous Fat in Bodybuilders

    Tesamorelin (Egrifta) also reduces VAT without the AAS side effects.
  13. M

    Bubble gut – VAT, SAT, both - or something else

    I'm assuming to check for herniated discs, disc degeneration, etc.? I've had painful episodes of lumbar issues on either side for the last several years from unintentional hyper-extending of the back during heavy lifts.
  14. M

    Bubble gut – VAT, SAT, both - or something else

    So I tried the exercise and can only fit one finger. But there is a ridge/bulge when I do which is described here. So I still don't know for sure. Can the abdominal region still stretch and distend without separation? Will need to get to a doc that can properly diagnose it.
  15. M

    Bubble gut – VAT, SAT, both - or something else

    Big difference from the above photos: 20lbs lighter and did not have this issue. I am perplexed as to why this wasn't diagnosed from my ultrasound I linked above since ultrasounds are used to diagnose IRD. Maybe because they were focusing on the internal organs.
  16. M

    Bubble gut – VAT, SAT, both - or something else

    So, if that's the case, I can't think of what caused it. What do I do to correct it? I don't squat these days, only work legs once a week and do leg press when I do. Where I was lifting heavy was doing standing BB curls. I am attaching actual photos of myself. No amount of dieting or cardio...
  17. M

    Metformin Decreases Aerobic Capacity, Muscle Mass and Testosterone

    No TRT while on metformin. My take: caution to euglycemic men in using metformin when not on TRT.
  18. M

    Metformin Decreases Aerobic Capacity, Muscle Mass and Testosterone

    While all my T levels across-the-board tanked after starting metformin, my IGF-1 levels sharply increased from a baseline of 250 to almost 400 after taking tesamorelin, ipamorelin/CJC-1295. I am not on testosterone therapy at the moment and feel that anyone that is on metformin should be...
  19. M

    Bubble gut – VAT, SAT, both - or something else

    Somehow I've developed a distended abdomen/hard belly and umbilical hernia (inverted navel) similar to the attached photo. I cannot tell if it's visceral adipose tissue (VAT) or subcutaneous abdominal adipose tissue (SAT) - perhaps both. I cannot see my abs even when I flex so there's SAT. It's...
  20. M

    Anyone succeeding in increasing T with Kisspeptin while on TRT

    Please share the doc's contact info. PM me, if you wish not to post here.
  21. M

    Iron Supplementation Protocol to Raise Ferritin FAST While on TRT: The Vorck Protocol

    Oral supplemental delivery of iron to raise ferritin levels has been a total failure for me. I have tried most every form of iron available in the states and abroad. Too much interference with gut bacteria, I suspect. The ONLY form, I believe, that may protect against the wrong gut bacteria...
  22. M

    Latest Update on Metformin

    Urgent: Does anyone know if Metformin discontinuation can cause rebound hyperglycemia? I am not diabetic but since July, had been taking Metformin for anti-aging, cardiovascular and many of its other benefits, however, because it was tanking my testosterone levels to all-time lows (see my post...
  23. M

    Metformin Lowers Testosterone?

    1 month update - officially in the tank whether it's from Metformin or not. Latest labs as of 12/6 are confirmatory for secondary hypogonadism: TT: 347 FT: 48.2 BIO: 99.2 SHBG: 30 E2: 11 Again, main concerns with proceeding with TRT: Given my history of hypercoagulopathy (past clots in both...
  24. M

    Anyone using T2 as a fat burner?

    A few doctors have touted the little-known thyroid hormone T2 to be used to help burn brown fat. Since there is only a tiny amount (8mg) in my NDT, I was thinking of adding it for the purported benefits...
  25. M

    Anyone succeeding in increasing T with Kisspeptin while on TRT

    https://www.peptidesciences.com/kisspeptin-10?queryID=330b154d45e02649aed60369fa245d8b&objectID=154&indexName=m1_default_products
  26. M

    Microdosing Enanthate

    I have a friend who's been on clomid and adex for several years and his T land E2 labs look great and he feels great. I just don't like the possible estrogenic aspect, but that hasn't seemed to be a problem for him, so, was thinking of giving enclomiphene a shot. If I did TE, I would be...
  27. M

    Microdosing Enanthate

    Due to my existing hypertension and past hypercoagulopathy, perhaps I would be best advised to try a SERM (i.e. enclomiphene) before jumping to frank TRT. Thoughts?
  28. M

    Metformin Lowers Testosterone?

    I am not T2D but prone to it, so unlike the test subjects, am taking Metformin electively as a geroprotective and prophylactic agent. The question is whether staying on it indefinitely will eventually necessitate TRT. I was already low normal and considering TRT [June, 2022 (pre-Metformin): TT...
  29. M

    Microdosing Enanthate

    What would be a "safe" low dose starting point for someone who has hypertension and past clotting issues, both of which are being managed by meds, exercise, diet? 20mg?
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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