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If injection frequency is equal, subcutaneous injections DO give you more stability than IM injections. EOD IM injections will be more stable than twice weekly subq though. There are some discrepancies between published studies and real life with regard to subq vs IM injection. In many men or...

Your free T is going to drop proportionately to your dose reduction. What type of free testosterone test did you have performed? A calculated free T based on 1500 ng/dL total and 67 nmol/L SHBG would be 25 ng/dL free T. That's probably a more reliable number, and if that was the trough of a...

By the way, I am a fellow GERD sufferer and have seen this worsen with TRT depending on the form and dosage. The effects of androgens vs estrogen here are distinct: estradiol relaxes the lower esophageal sphincter to promote more reflux events, while androgens somehow make the reflux more...

Actually, you might need your total T to be that high, or even higher, to have a decent free T with that high SHBG. You need to retest testosterone with a proper LC/MS method though so you can see where that actually sits. Your high E2 is also similarly artificially inflated by your high SHBG...

This doesn't seem entirely true. Without lifestyle changes, dose escalation is required over time to maintain the effects, until eventually tolerance builds to the highest tolerable dose and weight starts increasing again even as the drug is continued. This process seems to take a few years from...

Those don't exist. This is what you want for minimum gauge, maximum length for reaching the muscle at fattier sites like ventroglutes: Easy Touch U-100 Insulin Syringe with Needle, 27G 1cc 5/8-Inch

Bi-Mix is much more forgiving than Tri-Mix with dosing too high, because the medications have a shorter duration of action than the alprostadil in Tri-Mix. I think you would be fine to increase to 8-10 units without any risk of a 4+ hr erection.

I would suggest something like 20 mg every other day to start with. If you still find that intolerable, go even lower. There are diminishing returns moving from every other day to daily with cypionate, but you can also try that if you're willing. Run labs after 6+ weeks, note your progress with...

I don't remember what my protocol was like at the time of this experiment - currently doing 37.5 mg test cyp EOD for 131 mg weekly. I'm done with prop after the massive peak levels drove down my HDL, among other issues.

Dividing the same weekly dose into smaller, more frequent injections almost always reduces side effects compared to larger and less frequent injections. There are rare exceptions, but this is the rule.

It's pretty normal to see a transient increase in water retention and a transient increase in BP when you first start, before you adapt. Your baseline BP was already elevated, which gives you less headroom for these temporary effects. The "revved up" feeling is also temporary and will go away as...

Some people can dish it out, but they can't take it. I applaud your courage Vince.

No, so far my limited dabbling with both hormones only produced adverse effects. I plan to experiment with them some more in the future, perhaps in different forms like topical, but I don't think I am suffering in any major way without them.

This seems to be very individual. IIRC my pregnenolone dropped from 200 ng/dL to 30 ng/dL on TRT, so a very dramatic change there, while my DHEA-S dropped somewhat less from 150-200 to 80-100 ug/dL.

I tried it briefly, but my E2 was already high, so I'm not sure why I thought it would help. Mostly seemed to slow down my digestion and worsened GERD symptoms.

You can buy these from any Indian pharmacy like alldaychemist: https://www.alldaychemist.com/progynova-1mg-tablet.html https://www.alldaychemist.com/progynova-2-mg.html

This one isn't too bad in terms of the dosages but I'd still experiment with dropping it for a bit.

I forgot to mention magnesium. A decent sized dose of magnesium will leave me feeling sedated and apathetic for the entire day (or next day if taken at night). Feel much better getting this from food. Magnesium tests have been in the top half of normal range on carnivore diet.

There are many micronutrients in multivitamins that each make me feel like garbage in the high doses they typically use. I often wonder if other people are similarly affected and are not self-aware enough to notice the adverse effects. I've tested all of the nutrients independently and the...

What is MV? Do you consume stevia? Do you have anything to track sleep quality and SpO2 (to identify apnea) like an oura ring? How does that look? You said, "No other meds that cause libido side effects." Are you taking any other medications besides TRT?

I've also seen many reports of anhedonia which suggest it is having a broad effect in blunting the reward system, not food-specific.

Could be carrier oil or the excipients which almost always includes benzyl benzoate and benzyl alcohol. Try different carrier oils. If you want to try something thar doesn't include BB/BA, your ONLY (and I mean only) option is the hikma testosterone enanthate mentioned above.

The vast majority of us use MUCH smaller gauge insulin syringes with fixed 1/2" needles for shallow IM and subq injections. Depending on the location and your body composition, you can also use 27G 5/8" insulin syringes for shallow IM. I started using these for my ventroglute IM injections to be...

On that diet, it probably doesn't matter one way or the other: Plaque Begets Plaque, ApoB Does Not: Longitudinal Data From the KETO-CTA Trial

There are a laundry list of benefits described in that study and you got stuck on the high LDL? Are you aware of how poorly LDL cholesterol predicts CVD compared to 20 more impactful factors? If you're still concerned about it, take some lipid-lowering medication along with the diet. Dietary...

Dave said benefits arise only in a deficiency state, which again runs contrary to the Cortex video above, where he says serum levels don't predict who will benefit. Dave's overall position though is that DHEA supplementation, like pregnenolone, is rarely successful or well tolerated. From Dave...

He actually came here for DHEA quotes. @Guided_by_Voices is featured in the video. It's a curious thing to watch the evolution of TRT guru beliefs over time and how they drift to opposite sides of the same issue. Dave Lee for example was a huge proponent of supplementation with pregnenolone and...

I have great results carpet bombing everything with listerine and not chewing on the fermentable plant material, sugars, and starches which promote bacterial growth, acid production and biofilm / plaque accumulation. This approach yields healthy gums, zero inflammation, no cavities or fillings...

Everyone here is exhibiting remarkable restraint. No one knows everything, but the people responding know more than you. You must understand this on some level, or you wouldn't have come here to ask questions. A big chunk of your gains will be temporary and evaporate when you stop the 350 mg...

I can tell you're going to do this anyway, so in the interest of harm reduction, get these: https://www.amazon.com/PrimaForce-Yohimbine-Count-2-5mg-Capsules/dp/B079Y8BFBD/ That's the smallest and most precise dose available, which you are going to need to avoid the worst of the side effects...

It's not stronger, it's just a different class of medication than the PDE5 inhibitors and the dopamine agonist, to hit the problem from another angle. I'm not recommending it, because the benefit/side effect ratio is not favorable in most cases.