What No One Tells You about Testosterone Replacement Therapy

madman · Jun 22, 2025

Testosterone replacement therapy (TRT) is exploding in popularity among men. TRT has been touted online as a cure-all for everything from low energy to poor mood and even as a way to increase masculinity itself. But how much of the buzz is backed by science? Host Rachel Feltman talks with journalist Stephanie Pappas about the realities behind the trend. They explore who truly benefits from TRT, the overlooked risks—including fertility loss—and the rise of private clinics offering testosterone.

madman · Jun 22, 2025

Thread 'What Most Men Don’t Know about the Risks of Testosterone Therapy'

Jun 22, 2025

Abraham Morgentaler
Frederick Wu
Channa Jayasena
Joshua Halpern
Justin Dubin
Harrison Pope

By Stephanie Pappas

More Men Are Taking Testosterone—Without Knowing the Health Risks

To boost mood and manliness, men are spending lots of money on the hormone testosterone—yet they may see trouble instead of benefits

www.scientificamerican.com

Violet Frances; Source: Abraham Morgentaler (scientist reviewer)

Nelson Vergel · Jun 23, 2025

madman · Saturday at 1:00 PM

Thread 'Assessing Adherence to Guideline-Based Diagnosis and Treatment of Male Hypogonadism in the Age of Direct-To-Consumer Advertising'

Jul 19, 2025

Author Block: Petra E. Pederson, MD, PhD1, Jeremy Winkelman, MD1, Michelle Wong, MD1, Leah Puglisi, MS2, Matthew Jason Levine, MD, FACE3. 1Scripps Clinic/Scripps Green Hospital, La Jolla, CA, USA, 2Scripps Hub Academic Research Core (SHARC)/Scripps Health, San Diego, CA, USA, 3Scripps Clinic/Division of Endocrinology, La Jolla, CA, USA.
Disclosure Block: P.E. Pederson: None. J. Winkelman:None. M. Wong: None. L. Puglisi: None. M.J. Levine: None.

Background

Prescriptions for testosterone replacement therapy (TRT) for...