Recent content by mcs

With respect to the so-called anti-anabolic signaling of Metformin, might those of us on TRT be spared this effect?

This is an excerpt from a fire post. I have not been able to find who the poster was on this, but maybe somebody in this forum can help me find him. Trying to figure out why chronically low ferritin and other markers. “In general: Exogenous Testosterone increases EPO. Increased EPO causes the...

My most recent E2 was 53, the highest it's ever been. That's just on enclomiphene 25mg daily. My latest TT was 658, FT was 113 and SHBG was 43, FSH 5.4, LH 4.2, DHT 35. I'm sure the cream will further boost both TT and FT and drop SHBG, but with my E2 already elevated, I would be concerned. I...

Since the prescribed dose for the cream is 50mg/click, if I wanted to start at a lower dose, would applying eod be adviseable or would that cause uneven serum levels? Even on standard TRT doses (e.g. 100–200 mg/week), is it true that injectables typically produce higher free T and lower SHBG...

My concern regarding the topical T is the increased potential for hair loss due to more of an increase in DHT than in the oral or injectable - and the risk of BPH when I just had a scan that showed BPH. Should I opt then for the oral - or should I try out the topical first? I'd rather not have...

I take the compounded sublingual tablet of vardenafil/tadalafil (2.5mg/2.5mg) from Maximus before workouts for the NO release. I am not experiencing any side effects as I assume a total dose of 5mg of PDE5i is considered low dose. I would also like to further reduce my systolic BP but don't...

I have had several issues with Empower. Their customer service is not in-house and is outsourced to a third party which results in unacceptable delays and staff miscommunications. I have lost my sh*t more than once with their incompetence. Their shipping sucks as well, takes way too long to get...

Has anyone experienced an acute toxic reaction to any peptide compounds? Following is a cautionary tale and what happened in my case. 3 weeks ago, I trialed a small dose (100mcg) of ACE-031 (recommended dose is 1mg/week). This peptide is a myostatin inhibitor used for increasing lean mass. The...

Have there been any studies comparing your native Oral T to the native topical that show which one is more efficacious with the least amount of side effects?

Thanks. As with any compound, the only way to know how I will respond is to try it, just as with the enclomiphene. It took greater than 6 mos. to fully evaluate its effects. And if the gel fails to improve me any further, I have the enclomiphene as my baseline default.

Hoping Dr. Cam can chime in here. 65 y/o male. 1st phase of my recomp via a cut accomplished. Was finally able to drop 30lbs and bodyfat from 26% to sub 10% with no loss in muscle mass. Will be lean bulking with the goal to add 20lbs of LBM w/o adding bf via lean bulk Enclomiphene update...

I should've mentioned that I have trained consistently and hard at least 5 to 6 days a week for many years. That is how I was able to minimize the loss of lean mass. The goal here was to lose as much body fat as possible which I have done but want to be sub 10. Then to lean bulk as much as possible.

I have done a modified PSMF diet and have lost a total of 30lbs in 3 mos. Body fat went from 24% to 12%, muscle mass decreased about 6-7lbs. My waist was 36", now 31". Avg macros: Before diet: kcals: 2000-2350 pro: 165-175g cho: 50-75g fat: 125-150g During diet (after 6 weeks, increased pro...

The PSMF is a calorie, carb and fat restricted diet + high protein. I did not go strict and could not start at the 800kcal ceiling per day nor could I restrict fat to 20g or less. I started at a low of ~ 1000kcals and then took the protein intake a little higher to slow muscle catabolism from...