Recent content by Cataceous
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Should I up the cypionate dose?
No, modern oral forms are not hard on the liver. There are various testosterone undecanoate capsules, and I believe Maximus has a straight testosterone option. Someone here posted that even DIY is possible by ingesting testosterone with oil.- Cataceous
- Post #7
- Forum: Testosterone Basics & Questions
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Should I up the cypionate dose?
Splitting the dose does not affect your average level of testosterone. Currently you presumably have a relatively high level of testosterone in the day or two after each injection, but a low level in the day or two before each injection. For example, you might hit a peak of 750 ng/dL which...- Cataceous
- Post #5
- Forum: Testosterone Basics & Questions
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Should I up the cypionate dose?
Why not try splitting the dose, say into 25-30 mg twice weekly? This will dampen the high/low swings if you're currently injecting once a week.- Cataceous
- Post #2
- Forum: Testosterone Basics & Questions
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ED/low libido even with TRT
We should let others know that we have a spreadsheet posted for calculating free estradiol. Note that it is now attached to the post because the original links do not work: https://www.excelmale.com/forum/threads/spreadsheet-for-calculating-free-t-e2.17216/ The analogy of free/total estradiol...- Cataceous
- Post #19
- Forum: When TRT Is Not Enough (ED, Libido, & More)
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[urgent help] battling long long term effect of enclo
Though it might be too subtle to make a dent in such an extreme sleep disturbance, one thing you could try is measuring your serum progesterone, and if it's at the lower end of the range then supplement with some each night. Progesterone naturally opposes estradiol and is somewhat of a sleep aid...- Cataceous
- Post #2
- Forum: Testosterone Side Effect Management
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TRT Peaks and troughs or steady levels. Which is correct?
I'm not aware of anything new on the subject. The successes of testosterone nasal gel and oral testosterone seem likely to reduce interest in finding ways to more precisely mimic a normal diurnal rhythm in serum testosterone. You may have seen a study referenced by @madman showing that a...- Cataceous
- Post #5
- Forum: Testosterone Basics & Questions
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Aging and Testosterone dose
If one is looking to maintain free testosterone at a particular level then it's typical to need dose reductions over time. This is because the metabolic clearance rate of testosterone tends to decrease with age, which in turn increases free testosterone, as mentioned here. It's harder to...- Cataceous
- Post #3
- Forum: Testosterone Basics & Questions
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TRT Peaks and troughs or steady levels. Which is correct?
It's a good question, without a definitive answer. There's too much individual variation to say whether you'd find the differences to be subtle or profound. Neither modality produces a natural-looking diurnal rhythm in serum testosterone. However, men can have good results with either...- Cataceous
- Post #3
- Forum: Testosterone Basics & Questions
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What affects free testosterone under TRT?
Tempting though it is to veer into some caustic remarks, let's stick to the facts. Are your previous posts based on your understanding of the subject or are they AI generated? If the latter then which AI and which inputs?—And why didn't you disclose AI use at the time? Why don't you or the AI...- Cataceous
- Post #5
- Forum: Testosterone Basics & Questions
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What affects free testosterone under TRT?
The reasoning is incorrect and contradicts what is set out in the original post. A drop in SHBG only transiently affects free testosterone. At the new steady state free testosterone returns to its previous value, which is tied only to the testosterone production/dose rate and the clearance rate...- Cataceous
- Post #3
- Forum: Testosterone Basics & Questions
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Bromantane experiences ?
No, but it sounds interesting. For me, caffeine has more cons than pros, so it would be nice to have an alternative. I might get some bromantane to try next time I place an order with NS.- Cataceous
- Post #5
- Forum: Nutrition and Supplements
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Bromantane experiences ?
I see that Nootropic Source has the powdered form—in case anyone is looking for a pretty reliable source. A dosing summary from Grok: Typical oral doses for bromantane powder range from 50–100 mg per day, often taken once in the morning to avoid potential insomnia. A lower starting dose of 25...- Cataceous
- Post #3
- Forum: Nutrition and Supplements
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About to Start a New Protocol
It's actually neither, though the former—the thin, permeable skin—increases absorption efficiency. It's the prevalence of 5-alpha reductase in the scrotal skin that boosts production of DHT. There can also be a fair bit of aromatase, boosting estradiol as well in many cases. The testes don't...- Cataceous
- Post #47
- Forum: Testosterone Basics & Questions
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Enclomiphene Pharmacy Options
Defy Medical was using Taylor Made for enclomiphene until they eventually switched to Empower. The product from both of these places seemed to do the job. As I recall, Taylor Made at one time was having some legal issues, but maybe nothing affecting product quality. I'd say Empower is a slightly...- Cataceous
- Post #2
- Forum: Testosterone Basics & Questions
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Hypo since 20 y/o - now 30. Thoughts on this bloodwork?
There are pros and cons to either. Enclomiphene blocks the negative feedback from estradiol, which stimulates the HPTA. The higher LH/FSH then lead to increased testosterone, at least if the testicles are functioning well. Enclomiphene has the advantage of stimulating the entire HPTA. Clinical...- Cataceous
- Post #12
- Forum: Blood Test Discussion
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