Need Protocol advice

[Vince]

Here's one on zquiet.

 

[PAUL-E]

I read some reviews about the zquiet making peoples bottom teeth lose so I think I will pass on that version but I seen a adjustable moldable version http://www.amazon.com/Intelliguard-...ie=UTF8&qid=1463607633&sr=8-6&keywords=zquiet

My Dr. and I forgot to cover my AI dose I was thinking 3MG of exemestane the day after injection any thoughts?

 

[Vince]

Exemestane, I've never used an AI. My knowledge is limited, But I believe that exemestane needs to be taken daily, lowers your HDL and because of the high dose can hurt your liver?

 

[PAUL-E]

I thought exemestane wasn't as bad on lipids as other AI's and the half life is only 8.9 hours in men but it is effective past that due to it being a type 1 AI
CONCLUSIONS:


Exemestane appears to have a neutral effect on total cholesterol and HDL levels. Unlike tamoxifen's positive effect on LDL levels, exemestane does not significantly alter LDL levels. Tamoxifen on the other hand increases triglyceride levels, while exemestane results in a beneficial reduction in TRG levels. These data offer additional information with regard to the safety and tolerability of exemestane in postmenopausal breast cancer patients and support further investigation of its potential usefulness in the adjuvant setting.
http://www.ncbi.nlm.nih.gov/pubmed/16184460

Exemestane

The lipid effects of exemestane have, perhaps, been more closely studied than those of the other aromatase inhibitors. In animal studies, exemestane reversed the increase in LDL cholesterol and total cholesterol seen in ovariectomized cycling Sprague–Dawley rats
The effects of aromatase inhibitors on lipids and thrombosis
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361692/

The terminal half-life was 8.9 h. Maximal estradiol suppression of 62 ± 14% was observed at 12 h. The drug was well tolerated. In conclusion, exemestane is a potent aromatase inhibitor in men and an alternative to the choice of available inhibitors.
http://press.endocrine.org/doi/full/10.1210/jc.2003-031279

 

[ERO]

Great information!

I have also read that even though it has a short half-life, you do not need to take it daily as it takes your body 3-6 days to return to baseline after a single dose.

 

[PAUL-E]

Update: Good news the red cross machine must have been malfunctioning CBC results hemoglobin 16.1, hematocrit is 48.4 and with my new protocol I believe it will end up being lower that that next time around!

 

[PAUL-E]

I might have slightly crashed my estrogen I backed off to 3mg day after injection but have been getting a slight case of the rice crispy's you know snap crackle and pop also have been constipated a little. Mood has been ok as far as irritability but no morning wood.
would you guys take a week or two off the AI and see if there's a difference or cut down to 3mg 2x a week instead of 3x a week?
I will get E2 tested eventually I just didn't want to do it yet because I just started this new protocol and I might be adding nandrolone so for now I"m going buy how I feel/MW and adjusting later if needed based on how I feel and test numbers

 

[Vince]

Hopefully your new protocol of injecting three times a week is lowering your E2. So I don't think it would hurt to lower your AI. It sure seems like, when a person increases their injection days. It lowers their estrogen.
I would go with the 2x a week. That's my opinion.

 

[PAUL-E]

So I started my new protocol MY new protocol 3x a week
50mg testosterone total 150mg per week
300iu's of HCG total 900IU's a week
40MG of nandrolone deaconate total 120mg a week
no AI
I am a little over 3 weeks in the new protocol and I'm noticing my skin oil production is up, my acne is more and my erections are weaker which are signs of high estrogen for me don't know if I should just wait or make a change I have been thinking about lowering HCG dose to 200iu's 3x a week or start taking a low dose AI again 2x a week I know labs are best but I have an appointment coming up in about two months and would like to make changes now to get me closer.

 

[CoastWatcher]

So I started my new protocol MY new protocol 3x a week
50mg testosterone total 150mg per week
300iu's of HCG total 900IU's a week
40MG of nandrolone deaconate total 120mg a week
no AI
I am a little over 3 weeks in the new protocol and I'm noticing my skin oil production is up, my acne is more and my erections are weaker which are signs of high estrogen for me don't know if I should just wait or make a change I have been thinking about lowering HCG dose to 200iu's 3x a week or start taking a low dose AI again 2x a week I know labs are best but I have an appointment coming up in about two months and would like to make changes now to get me closer.

That's what Discountedlabs.com is set up for. Don't guess, test.

 

[PAUL-E]

That's what Discountedlabs.com is set up for. Don't guess, test.

I'm still in between jobs at the moment and am just trying to save I'm that type of guy that needs the full picture I couldn't do just estrogen I would have to do testosterone free and total, SHBG, estrogen sensitive, CBC, and CMP my next appointment blood draw I also plan on checking progesterone and prolactin as well. That being said I know your right just thought about making some changes now like the lower HCG dose

 

[PAUL-E]

Just an update found an old mouthpiece from when I had a slipped disc in my jaw, I've been using at night and it has helped open up my breathing. I also dropped the HCG two 200iu's 3x a week MWF, it's been a week and I noticed my skin is far less oily, less acne and better erections so I think I was right and was converting too much to estrogen we will see wit more time.

 

[MikeXL]

You mentioned that your only concern with Nandrolone is its effect on HCT? What do you know about its effect on HCT in comparison to testosterone?

 

[PAUL-E]

I'm not an expert but considering nandrolone is prescribed for anemia (low red blood count) I would think it would raise hematocrit more than testosterone but the effect would probably dose dependent.