Need Protocol advice

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PAUL-E

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I have been thinking about talking to my DR. and changing my protocol
reasons why are
1st
I didn't have the traditional CYP2D6 test I used my family tree DNA and uploaded it to a different site some tests said there was insufficient data but others like coffee suggested that caffeine would have little to no effect on me which I can vouch for that combined with my TRT dose and numbers I get leads me to believe I might be a fast metabolizer.
2nd reason is I might be adding Nandrolone for medical reasons and my only real concern with nandrolone is it effects on hematocrit.

My current protocol is 110mg test with 500IU 2x a week Monday morning and Thursday 3MG exemestane ED night equaling a total weekly amount of 220mg testosterone cyp and 1000iu's of HCG. I hate injecting and yet look forward to it. I have used this sites resources and learning about insulin needles has helped a ton but to be honest I still don't want to inject more than 3x a week.

New protocol idea is 60mg test with 250-300iu's HCG 3x a week Monday morning Wednesday afternoon and Friday night equaling a total weekly amount of 180mg test and 750-900iu's HCG a week
keeping 3MG exemestane ED unless signs of low E2 or blood work then try 3MG EOD

I was hoping for some feedback and opinions
Thanks
 
Defy Medical TRT clinic doctor
So going from 220 to 180 total week should have less of an effect on HCT as would increasing from 2 to 3 times per week. I would try to keep the same total HCG.

what is the reason to use nandrolone? I understand that it is near impossible to get someone to prescribe it
 
So going from 220 to 180 total week should have less of an effect on HCT as would increasing from 2 to 3 times per week. I would try to keep the same total HCG.

what is the reason to use nandrolone? I understand that it is near impossible to get someone to prescribe it
My hope in changing protocol would lead to lower E2 conversion and hematocrit although the highest I have seen my hematocrit was 52.7 a little over 4 months after a double red donation.
Nandrolone for CRPS/RSD
https://www.excelmale.com/forum/showthread.php?6554-Nandrolone-for-CRPS-RSD
 
To be honest right now I am not sure my last sensitive E2 was high 51.2 8-35 but I was unintentionally taking .5-1mg a day when I thought I was taking 3MG a day

I was hoping to start the nandrolone with new protocol and about 8 week later recheck everything
 
A possible big bump in the road went to the red cross to donate whole blood and my hemoglobin was 19.8 time that by three to get hematocrit and that's 59.4! they didn't have time for a double red so I did a whole blood donation and in over a week I will be getting my hematocrit checked. I have not experienced any headaches or chest pain and I noticed there was a blood sample forgot in the machine before my sample was tested so I don't know if that would effect anything, either way I will be contacting my TRT DR about my protocol so I would appreciate any impute if you think my idea is good or if you would recommend different doses. Thanks
 
whole blood donations drop hematocrit an average of 3% which would be about 1.7 for 59.4
a new estimate would be 57.7 correct?
I'm not looking for medical advice or anything just opinions based on experience
Thanks
 
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Your new protocol looks solid. The Extremestane dose looks high, but you also seem to be a high converter to E2 so it may be fine as well. I don't know if there is any reliable method or formula to predict a correlation between T dose and Hematocrit (Dr. Saya may know if one exists). In other words, you may need to just try it and see instead of plugging in the numbers to tell you that reducing your T dose by "X" will result in lowering your Hematocrit by "Y."
 
What levels are your platelets, remember to drink lots of water and maybe you should take a daily aspirin. I do like your new protocol, but in all truth I do believe we only need to inject every 3 1/2 days. Personally I'm not convinced that we need to inject more. Hopefully you will prove me wrong. :eek:
 
It is true, as Vince noted, that most don't have to inject more than twice a week, but the one thing I have learned is that everyone is different. My daily injections have been a great success, but I realize most men would resist that idea. Still, for me it has become second nature. I would think you'll notice an improvement. I do hope you can cut your AI back.
 
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I would like to avoid an AI all together one day if possible but is 3mg of aromasin/exemestane really a lot? It's about 1/8 of a pill.

Just a side note if you donate blood make sure the iodine is somewhat dry before they stick you!
Thanks for all your advise/opinions I will update with changes
 
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Update: I talked with my DR. new protocol 50mg and 300iu HCG 3x a week MWF totaling 150mg testosterone and 900iu's of HCG. When I told him what the red cross said 19.8 he in a respectful way indirectly asked me if I may have accidently taken more than prescribed since I haven't had an issue with hematocrit before, which the answer is no the only difference in protocol was the addition of HCG and that fact I started crushing my AI pills and was unintentionally under dosing. I am thinking the 19.8 might have been an error due to the dramatic increase and I don't believe I was on HCG long enough to make such a dramatic difference so I think high estrogen might be the culprit if 19.8 is accurate I am getting CBC checked at the end of the week so we will see. any ideas what might have caused the dramatic increase?
 
It may just be testing error. The hematocrit tests at the Red Cross are somewhat of a "quick and dirty" test mainly designed to be sure donors are not anemic before they donate rather than being designed to be the ultimate in accuracy.
 
When I talked to my DR he also mentioned sleep apnea which I blew off at the time but looking into it and talking to my wife she said I snore sometimes(maybe more she falls asleep in like a minute and me in an hour). Last night paying attention I noticed my lower jaw sits back and obstructs my airway moving my lower jaw forward opens the airway and I notice I get a lot more air and breath easier some other factors may be that due to injury and medication I went threw what I call a reverse recomp and I slipped a disc in my jaw before.
 
The price is good, looks like a tooth guard for people who grind their teeth at night. I wonder if it will stay in place while you're sleeping.
 
When I talked to my DR he also mentioned sleep apnea which I blew off at the time but looking into it and talking to my wife she said I snore sometimes(maybe more she falls asleep in like a minute and me in an hour). Last night paying attention I noticed my lower jaw sits back and obstructs my airway moving my lower jaw forward opens the airway and I notice I get a lot more air and breath easier some other factors may be that due to injury and medication I went threw what I call a reverse recomp and I slipped a disc in my jaw before.

My TRT doc also mentioned sleep apnea- and since I am a heavy snorer I went to see a ENT. They did a sleep study and I have borderline moderate obstructive sleep apnea. Meaning my apnea wakes me up 14.9 times per hour. Below 5 is considered normal. I have been using a CPAP machine since Saturday and so far so good. I'm averaging less than 3.8 apnea events now. My nightly results get sent to my ENT daily so he may tweek the CPAP pressure to get that even lower. btw- the CPAP pretty much eliminates snoring.
 
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