Pramipexole

[nippy]

I'm looking to try pramipexole to boost dopermine and hopefully give me some libdio... I'm finding it impossible to get hold of ..

 

[Nelson Vergel]

If you are diagnosed with restless leg syndrome, it is not hard to get by prescription.

 

[nippy]

I don't have it .. . I'm thinking of caber first but lots of people day it's very harsh on the body

 

[HarryCat2]

My sleep specialist tells me it is no longer recommended for RLS due to augmentation, a worsening of RLS with long term use. In any event there was a lot of discussion about using dopamine agonists to boost libido on the TRT forums about 10 years ago and I don't recall anyone reporting positive results at doses below what is used to treat Parkinson's (RLS doses were much smaller).

 

[MilkMan]

I've used it without seeing any effect on libido.

Are you on TRT?

 

[Nelson Vergel]

Guys, be careful with lowering your prolactin too much.

Men's Sexual Problems Linked to Low Prolactin Levels - Excel Male TRT Forum

This is an article from 2013 that I found very interesting regarding the impact of low prolactin on men. A study involving nearly 3,000 European men aged 40 to 79 has revealed that low levels of the hormone prolactin are linked to sexual and psychological health issues in men. Traditionally...

www.excelmale.com

Low Prolactin Is Associated with Sexual Dysfunction & Psychological/Metabolic Issues - Excel Male TRT Forum

I caution men who are using cabergoline to be careful not to bring their prolactin down too low. Men use cabergoline to decrease their prolactin after a study showed that this would improve orgasms, but now a new study shows that too low of a prolactin blood level can create problems...

www.excelmale.com

Prolactin: Should Men with Erectile Dysfunction Be Tested ? - Excel Male TRT Forum

Prolactin is a hormone produced in the pituitary gland that is known for supporting lactation in women but also have many other functions on immune response, myelin coating on nerves, and also enhances LH receptors on testicular Leydig cells so that testosterone can be produced. Prolactin...

www.excelmale.com

 

[MilkMan]

Thanks, Nelson.

I ran this through PubMed and found this:

Neuroendocrine and side effect profile of pramipexole, a new dopamine receptor agonist, in humans - PubMed

Pramipexole did in fact reduce prolactin levels.

 

[MNguy]

Last I checked, allday chemist has it available

 

[nippy]

I've used it without seeing any effect on libido.

Are you on TRT?

Sorry missed this. Yes I am. Just changed from IM to sub q and the rush from dopamine was amazing. I felt like the old me . I had a sex drive ... I obviously need to increase my dopamine now it's subsided

 

[Gman86]

Sorry missed this. Yes I am. Just changed from IM to sub q and the rush from dopamine was amazing. I felt like the old me . I had a sex drive ... I obviously need to increase my dopamine now it's subsided

Why would subQ injections result in more dopamine over IM injections?

 

[nippy]

Why would subQ injections result in more dopamine over IM injectionsolol I was talking to a guy who has the same issue . He said when it happened to him he spoke to his endo who said it's a change of absorption and that increases dopermine. He said I bet it lasted about a week and it did

 

[MIP1950]

I tried caber about two years ago(rx from my urologist). All it did was worsen my sleep and made me irritable and edgy.

 

[nippy]

I tried caber about two years ago(rx from my urologist). All it did was worsen my sleep and made me irritable and edgy.

Well I've just read wellbutrin can help with dopamine but going off all the people I've spoke to it's made them worse

 

[MIP1950]

Well I've just read wellbutrin can help with dopamine but going off all the people I've spoke to it's made them worse

Since I don't know what you can order in the UK, I was thinking of tongkat ali or tribulus or mucuna pruriens. Never used any of them but they've been used by indigenous cultures. Tongkat Ali(Longjack), if it's standardized, might be worth trying.

 

[Cataceous]

I'll put in a plug for selegiline, aka L-deprenyl. It's a good option to consider if you're no longer on the young side. It counteracts the age-related reduction in dopamine and even improves longevity in some animal studies. Although it's less known for reducing prolactin, it almost certainly has that effect. Ideally you'd get it through a doctor, but you can buy it directly from AllDayChemist.

 

[nippy]

Since I don't know what you can order in the UK, I was thinking of tongkat ali or tribulus or mucuna pruriens. Never used any of them but they've been used by indigenous cultures. Tongkat Ali(Longjack), if it's standardized, might be worth trying.

Thanks for the advice. I've been told addrell

Since I don't know what you can order in the UK, I was thinking of tongkat ali or tribulus or mucuna pruriens. Never used any of them but they've been used by indigenous cultures. Tongkat Ali(Longjack), if it's standardized, might be worth trying.

Thanks for the advice . I've just been told Adderall is helpful with libido... Did a quick Reddit search just to get the basics and whhoooooo very interesting

 

[MIP1950]

A psychiatrist wanted to prescribe it for my depression but I know about the drug. Speed, actually. Yes, it will give you a major dopamine bounce but it would be like a nuclear explosion in your brain, unless you have ADHD/ADD or some other disorder where dopamine is down regulated. @Cataceous is right about selegiline. I've read about it and it would seem to be a better way to go if you want to use a pharmaceutical.

 

[nippy]

I do have personally disorders... I think it's ADD but they think it's a personality disorder... My niece has ADHD and the more I read about ADD the more sure I am I have it .

 

[nippy]

A psychiatrist wanted to prescribe it for my depression but I know about the drug. Speed, actually. Yes, it will give you a major dopamine bounce but it would be like a nuclear explosion in your brain, unless you have ADHD/ADD or some other disorder where dopamine is down regulated. @Cataceous is right about selegiline. I've read about it and it would seem to be a better way to go if you want to use a pharmaceutical.

After stopping the srris a few years back. The
lack of dopamine is now obvii

 

[MIP1950]

I do have personally disorders... I think it's ADD but they think it's a personality disorder... My niece has ADHD and the more I read about ADD the more sure I am I have it .

If your doctor would prescribe Adderall...or refer you to a neurologist or psychiatrist. The psychiatrist I saw screened me for ADHD/ADD and my score was low, but his backround was in research, so he asked if I wanted to try it but ultimately I didn't. My two major concerns was that it would make me manic and worsen my Tourette Syndrome. I already tic a lot; noises and movements. I've had TS since I was three. 68 years.