Are you tired even with normal testosterone? Adrenal fatigue may be the problem.

[Country23030]

Among the best probiotics are VSL#3, Gardenof Life

$1 a day a little too much for me.

 

[gerardo]

Paper that validates saliva cortisol testing

Cortisol in Saliva — Reference Ranges and Relation to Cortisol in Serum

Hello Nelson. Do you have the link to this article? It is not opening. Thanks

 

[Nelson Vergel]

Eur J Clin Chem Clin Biochem
. 1995 Dec;33(12):927-32. doi: 10.1515/cclm.1995.33.12.927.

Cortisol in saliva--reference ranges and relation to cortisol in serum

E Aardal 1, A C Holm

Abstract
The aim of this study was to establish morning and evening reference ranges for cortisol in saliva. Another objective was to compare the concentrations of the mainly free cortisol in saliva to those of total cortisol in serum as determined with a commercial radioimmunoassay. The concentrations were determined in matched samples of saliva and serum collected at 8 am and 10 pm from 197 healthy volunteers. The saliva samples were stable for at least 7 days at room temperature and for 9 months at -20 degrees C. Reference ranges, the central 95%, were estimated to 3.5-27.0 nmol/l at 8 am and < 6.0 nmol/l at 10 pm. The intra-assay coefficient of variation (CV) was below 5% and total CV below 10%. The relation between the cortisol concentrations in serum and saliva was non-linear with r = 0.86 for serum concentrations < 450 nmol/l and r = 0.44 for serum concentrations > or = 450 nmol/l. In conclusion, the satisfactory precision of the analysis and the simple non-invasive sampling procedure suggest that saliva may be used for cortisol measurements in situations where blood sampling is difficult to perform.

 

[Nelson Vergel]

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Tired of Being Tired?- Get a Comprehensive Fatigue Panel

This article described blood tests that can help to diagnose the causes for your fatigue. Fatigue is can be very frustrating for many people since it can have several causes. There's the normal tiredness we feel at the end of every day, the tiredness that comes from being a hard-working person...

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[gerardo]

Eur J Clin Chem Clin Biochem
. 1995 Dec;33(12):927-32. doi: 10.1515/cclm.1995.33.12.927.

Cortisol in saliva--reference ranges and relation to cortisol in serum

E Aardal 1, A C Holm

View attachment 14164

Abstract
The aim of this study was to establish morning and evening reference ranges for cortisol in saliva. Another objective was to compare the concentrations of the mainly free cortisol in saliva to those of total cortisol in serum as determined with a commercial radioimmunoassay. The concentrations were determined in matched samples of saliva and serum collected at 8 am and 10 pm from 197 healthy volunteers. The saliva samples were stable for at least 7 days at room temperature and for 9 months at -20 degrees C. Reference ranges, the central 95%, were estimated to 3.5-27.0 nmol/l at 8 am and < 6.0 nmol/l at 10 pm. The intra-assay coefficient of variation (CV) was below 5% and total CV below 10%. The relation between the cortisol concentrations in serum and saliva was non-linear with r = 0.86 for serum concentrations < 450 nmol/l and r = 0.44 for serum concentrations > or = 450 nmol/l. In conclusion, the satisfactory precision of the analysis and the simple non-invasive sampling procedure suggest that saliva may be used for cortisol measurements in situations where blood sampling is difficult to perform.

Thank