Estrogenic effects - always nipples and gaining fat?

Susabar34

New Member
Does elevated estradiol or zuclompihene isomer effects always include gaining fat and nipples sensitivity? My doc hasn't checked my estradiol during 3year clomid therapy, I was experiencing then some unpleasnt effects like mood swings, irritability, depression and I am curious if it could be from zuclomihene or too much of estardiol, during therapy I have't any problem with gaining fat or nipples sensityvity
 
I've already send a post there:

"In my case clomid has elevated my total testosterone well. I felt improvement, but I was still complaining on low T symptoms, especially fatigue, libido, erection quality, depression and sleep disorders. The longer I was taking it, the positive effects were slowly dissapearing. I started 50mg eod, after 3,5 months 50mg 5 times per week, after another 3,5 months 50mg 4 times per week etc. My total testosterone was 700-900 ng/dL during therapy. Is there any managment of existing hypogonadal symptoms despite high total T, which my endocrynologist hasn't tried with me, or I should switch clomid to testosterone? He checked only total testosterone during treatment with this drug.

Before starting taking clomid, I had detailed diagnostic in the hospital, macroandenoma had been found on my pituitary (acromegaly) I was prescribed testosterone 100mg e14d, I was taking it for 10 weeks, until surgery and I felt much more improvement comparing to clomid. Surgery was succesfull but I still have to take Sandostatin Lar 30mg to keep my IGF-1 in normal range. 6 months After surgery my tesosterone raised to 400ng/dl but hypogonadal symptoms were still existing so my physician decided to give me clomid. "
 
I haven't asked there about estrogenic/zuclompihene effects. Vince asked about my clomid protocol, so I quoted myself because I wrote there about it.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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