Mixed Pregnyl (HCG)

Ampoules are single dose containers, so they can not be stored for later use once the neck is broken. This is why the manufacturer included a preservative-free diluent.

Thanks Empower!

Had not meant to store an opened ampoule in the fridge, but three syringes filled with 500iu each. Would that work?
I had to dose that 500iu eod instead of 1500iu twice a week to lower E2.
 
Since you will be reconstituting with a preservative-free diluent, it is not recommended to store the excess medication in a syringe. If the diluent was Bacteriostatic Water I would be more comfortable with the drug being stored in a syringe. I would purchase lyophilized HCG that comes in a vial with Bacteriostatic Water for Reconstitution in the future. IMG_0326.webp
 
Hi Empower!

Where I live (northern eourope) there is only pregnyl in ampoule, 1500IU or 5000IU and these are for fertility problems. I can buy empty vials and bacteriostatic water, but only at the black market i think. But I hold on to check if it is possible to buy it in the pharmacy so i can mix it in empty vials.

And we only have two choises of testosteron, gel or Nebido.
And it seems that Nebido is not working so well. Have read about many people in my country who are treated with Nebido who crashes at the end before the next injection, they may also go and give blood quite often. High E2 those first few weeks that will be difficult to treat when the levels go up and down.
 
What is the consensus on when to inject hCG while on TRT? Some say on days 5 and 6 before the weekly test injection. Others seem to prefer that the doses are spaced out a bit more between injections.

Which have you found to be more effective?
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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