Anyone using Berberine HCl instead of Metformin for insulin control?

I have been researching this ... looks very promising ... less side effects.

Sincerely ... DK

Could you expand on why you are exploring Berberine? What are your fasting and post-prandial blood sugars like? What is your HgbA1c? What is your diet like? Your exercise habits? Are you on any medications?

As to your question, this has been addressed previously in several threads. The following is a portion of my response to a similar question from the thread "Anyone currently using metformin and getting it online?":

"Berberine is not something to fool around with. It does seem to work to some degree, but it may do so by affecting your liver in potentially dangerous ways. It has not undergone the rigorous testing process to which all FDA-approved prescription drugs are subjected, and my view is that it currently should not be prescribed for the treatment of diabetes or pre-diabetes.

Metformin is a good drug with a good track record. It has been around for many decades and is generally very well-tolerated with almost no serious side effects noted except for the rare possibility of lactic acidosis in those with existing kidney disease. Metformin has occasionally been linked in the literature to a decrease in serum Vitamin B-12, so one might want to have that tested when starting metformin to have a baseline (and perhaps take a low-dose B-complex vitamin or multivitamin with Bs if you don’t already; high doses of B-12 probably aren’t indicated).

I am on metformin and it enabled me to achieve basically normal blood sugars. You may want to consider discussing this with a doctor with experience in the treatment of pre-diabetes and diabetes. For further general information and discussions of treatment protocols for pre-diabetes, see this site and Dr. Richard Bernstein's seminal book on the subject, Diabetes Solution.

You should consult your doctor before taking any medication, including metformin."
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
4
Guests online
567
Total visitors
571

Latest posts

Back
Top